Infection Without Sepsis

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Condition / disease
Location
Status: Not yet recruiting

Vascular Events in Noncardiac Surgery Patients Cohort Evaluation Study 2

VISION-2 is an international, multi-site, prospective observational cohort study of 20,000 patients undergoing noncardiac surgery. Continuous biometric data will be blindly collected for the first 30 postoperative days, in hospital and at home, using Vitaliti™. Following study enrollment and baseline data collection, follow up visits will occur in-hospital, at 30-days, and 1-year post-operatively. VISION-2 has 3 primary objectives, among participants who underwent noncardiac surgery, the investigators will: 1) determine the pattern and frequency of physiological precursors (i.e., biophysical signals) to MINS, BIMS, sepsis, and infection without sepsis; 2) build prediction models from these biophysical signals and their extracted features through supervised machine learning, for the prediction and early detection of those complications; and 3) build a biobank for evaluation of novel biomarkers.

Participants needed: 20,000
Trial details
Age: 65+Biological sex: AllType: ObservationalSponsor: Hamilton Health Sciences CorporationUpdated: Apr 14, 2026Locations: 3
Eligibility criteria

age ≥65 years; [+2]

hearing aid(s) or cochlear implant(s) in left ear; [+6]