Vascular Events in Noncardiac Surgery Patients Cohort Evaluation Study 2

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age65+
SponsorHamilton Health Sciences Corporation

About this trial

VISION-2 is an international, multi-site, prospective observational cohort study of 20,000 patients undergoing noncardiac surgery. Continuous biometric data will be blindly collected for the first 30 postoperative days, in hospital and at home, using Vitaliti™. Following study enrollment and baseline data collection, follow up visits will occur in-hospital, at 30-days, and 1-year post-operatively.

VISION-2 has 3 primary objectives, among participants who underwent noncardiac surgery, the investigators will: 1) determine the pattern and frequency of physiological precursors (i.e., biophysical signals) to MINS, BIMS, sepsis, and infection without sepsis; 2) build prediction models from these biophysical signals and their extracted features through supervised machine learning, for the prediction and early detection of those complications; and 3) build a biobank for evaluation of novel biomarkers.

Eligibility criteria

Qualifiers

age ≥65 years;

underwent non-cardiac surgery with general, neuraxial, local, or regional anesthesia; and

expected length of hospital stay of 3 or more days

Disqualifiers

hearing aid(s) or cochlear implant(s) in left ear;

pacemaker/implantable cardioverter-defibrillator (ICD);

externally programmable cerebrospinal fluid shunt;

deep brain stimulator;

Trial design

Treatments tested in this trial

  • Continuous vital signs measurement device

Treatment groups

No treatment groups listed

Sponsors and collaborators

Hamilton Health Sciences Corporation

Lead sponsor

McMaster University

Collaborator

Canadian Institutes of Health Research (CIHR)

Collaborator

Population Health Research Institute

Collaborator