Jaundice

5

Review clinical trials related to Jaundice. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Impact of Prepartum Intravenous Fluid Intake on Newborn Weight Loss in the First Days of Life

At birth, the infant's weight was measured daily to assess the adequacy of nutritional intake. This indicator can be influenced by various factors related to the mother, her pregnancy, as well as medical interventions during the pre-delivery phase, such as pre-partum maternal fluid intakes, and the subsequent feeding method chosen for the newborn infant. This study aimed at exploring the association between maternal vascular fluid loading during labor in the pre-partum period and neonatal weight loss in the first two days of life. The study focuses on infants fedded with infant formula. This observational, retrospective, single-center study was carried out at the Amiens University Hospital Center. The participants were mothers aged 18 and older, hospitalized in the maternity ward following full-term delivery (\> 37 weeks of gestation). Data were collected through the medical records of the patient and their newborn. The investigators hypothesize that a relationship may exist between maternal pre-partum vascular fluid loading and neonatal weight loss in the first two days of life, in infants fed with infant formula. These results could raise awareness and help adapt medical and parental approaches to neonatal weight loss.

Participants needed: 200
Trial details
Age: 18+Biological sex: FemaleType: ObservationalSponsor: Centre Hospitalier Universitaire, AmiensUpdated: Nov 21, 2025Locations: 1
Eligibility criteria

Full-term delivery (≥37+0 SA) [+3]

Mother under guardianship [+7]

Status: Recruiting

SSM Predicts Outcomes of CLD Inpatients With Acute Liver Injury

In this study, a single non-invasive tool, spleen stiffness measurement (SSM), was used to monitor the disease regression of inpatients with chronic liver disease (CLD) and acute liver injury. The present study aimed to establish an early diagnosis warning model for acute-on-chronic liver failure (ACLF) by SSM and investigate the effect of dynamic changes in SSM on the short-term prognosis (28-day, 90-day morbidity and mortality) of inpatients with CLD and acute liver injury.

Participants needed: 411
Trial details
Age: 18-80Biological sex: AllType: ObservationalSponsor: Nanfang Hospital, Southern Medical UniversityUpdated: May 21, 2025Locations: 1
Eligibility criteria

Age between 18 years and 80 years [+2]

Prior surgery of liver diseases before enrollment such as liver transplantation,... [+7]

Status: Not yet recruiting

Value of Transcutaneous Bilirubin Devices

The goal of this observational study is to compare the value of transcutaneous bilirubin devices versus serum bilirubin in jaundiced neonates

Participants needed: 80
Trial details
Age: Up to 28Biological sex: AllType: ObservationalSponsor: Assiut UniversityUpdated: Jul 30, 2024Locations: 1Duration: 25 Days
Eligibility criteria

They were born between 35 and 42 weeks of gestation, had a birth weight of more...

Exclusion criteria are severely ill neonates, neonates with a lethal congenital...

Status: Not yet recruiting

The LINFU® U.S. Registry in Patients With Clinical Signs and/or Symptoms of Disease

Evaluate LINFU® in patients who exhibit signs or symptoms (i.e. jaundice, abdominal pain, weight loss, nausea and vomiting etc.) suggestive of pancreatic cancer (PDAC) or have evidence of imaging studies suggestive of PDAC.

Participants needed: 1,000
Trial details
Age: 18-90Biological sex: AllType: ObservationalSponsor: Adenocyte, LLCUpdated: May 14, 2024Duration: 5 Years
Eligibility criteria

Both males and females will be enrolled and must be at least 18 years of age and... [+3]

Patient under the age of 18 and over the age 90 [+7]

Status: Recruiting

Physiologically Based Cord Clamping To Improve Neonatal Outcomes In Moderate And Late Preterm Newborns

Before birth, the baby's lungs are filled with fluid and babies do not use the lungs to breathe, as the oxygen comes from the placenta. As delivery approaches, the lungs begin to absorb the fluid. After vaginal delivery, the umbilical cord is clamped and cut after a delay that allows some of the blood in the umbilical cord and placenta to flow back into the baby. Meanwhile, as the baby breathes for the first time, the lungs fill with air and more fluid is pushed out. However, it does not always work out that way. A baby born prematurely may have breathing problems because of extra fluid staying in the lungs related to the immaturity of the lung structure. Thus, the baby must breathe quicker and harder to get enough oxygen enter into the lungs. The newborn is separated from the mother to provide emergency respiratory support. Although the baby is usually getting better within one or two days, the treatment requires close monitoring, breathing help, and nutritional help as the baby is too tired to suck and swallow milk. Sometimes, the baby cannot recover well and show greater trouble breathing needing intensive care. This further separates the mother and her baby. A possible mean to help the baby to adapt better after a premature birth while staying close to the mother is to delay cord clamping when efficient breathing is established, either spontaneously or after receiving breathing help at birth. In this study, we intend to test this procedure in moderate or late preterm infants and see whether the technique helps the baby to better adapt after birth and to better initiate a deep bond with the mother.

Participants needed: 180
Trial details
Age: 32-36Biological sex: AllType: InterventionalSponsor: Queen Fabiola Children's University HospitalUpdated: Mar 5, 2024Locations: 2
Eligibility criteria

The delivery takes place between 32 0/7 and 36 6/7 weeks of gestation [+1]

Fetal anomalies including congenital malformations, anemia, and growth restricti... [+7]