Ketone Monoester

2

Review clinical trials related to Ketone Monoester. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

The Effects of Exogenous Ketones on Cognitive Function

The purpose of this study is to evaluate the acute effects of exogenous ketone monoester (KME) supplementation on cognitive function in three groups of adults aged 19-55 years: (1) obese, sedentary individuals; (2) lean, sedentary individuals; and (3) lean individuals who engage in regular physical activity (e.g., collegiate or amateur athletes). The main questions it aims to answer are to: * Assess the effects of acute KME supplementation versus placebo on cognitive, sensorimotor, and functional outcomes within groups. * Compare cognitive performance across the three groups. The primary outcome is cognitive performance assessed using the NIH Toolbox Cognition Battery. Secondary Outcomes include sensorimotor performance, measured using the Senaptec Sensory System, and driving performance, assessed with a driving simulator.

Participants needed: 45
Trial details
Age: 19-55Biological sex: AllType: InterventionalSponsor: University of Alabama at BirminghamUpdated: Jul 13, 2026Locations: 1
Eligibility criteria

Age 19-55 years [+3]

Diagnosed neurological conditions (e.g., Parkinson's disease, multiple sclerosis... [+4]

Status: Recruiting

The Effects of Exogenous Ketones on Cognitive Function

The purpose of this study is to evaluate the acute effects of exogenous ketone monoester (KME) supplementation on cognitive function in three groups of adults aged 19-55 years: (1) obese, sedentary individuals; (2) lean, sedentary individuals; and (3) lean individuals who engage in regular physical activity (e.g., collegiate or amateur athletes). The main questions it aims to answer are to: * Assess the effects of acute KME supplementation versus placebo on cognitive, sensorimotor, and functional outcomes within groups. * Compare cognitive performance across the three groups. The primary outcome is cognitive performance assessed using the NIH Toolbox Cognition Battery. Secondary Outcomes include sensorimotor performance, measured using the Senaptec Sensory System, and driving performance, assessed with a driving simulator.

Participants needed: 45
Trial details
Age: 19-55Biological sex: AllType: InterventionalSponsor: University of Alabama at BirminghamUpdated: Jan 7, 2026Locations: 1
Eligibility criteria

Age 19-55 years [+3]

Diagnosed neurological conditions (e.g., Parkinson's disease, multiple sclerosis... [+4]