Knee Replacement, Total

2

Review clinical trials related to Knee Replacement, Total. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Knee Replacement Rehabilitation Care Pathways

Previous research has shown that use of rehabilitation (including physical therapy) and the recovery of function after knee replacement surgery may differ depending on patients' race, sex, income or insurance, and geographic location. In this study, the investigators will develop and test a new care pathway for knee replacement rehabilitation that is designed to maximize functional recovery for all patients and reduce differences between different groups of patients. Findings from this project will lead to improved rehabilitation quality after knee replacement surgery.

Participants needed: 275
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of PittsburghUpdated: May 20, 2026Locations: 1
Eligibility criteria

scheduled to receive unilateral TKA surgery at a University of Pittsburgh Medica... [+1]

does not undergo planned surgery [+1]

Status: Recruiting

Comparing Articular Noise and Its Perception Between Two Different Types of Total Knee Arthroplasty

Some patients complain of articular noise (such as clicking, snapping, cracking or popping) after a total knee replacement. Controversy remains about whether there is a correlation between articular noise and worse outcomes following a knee replacement. A study by Nam et al. on 1540 patients revealed an association between noise and residual symptoms 30 days after they received a total knee replacement. Conversely, a study by Kuriyama et al. on 60 patients revealed no correlation between noise and patient satisfaction after 1 year of receiving a total knee replacement. The incidence of noise following a knee replacement has rarely been studied as a primary outcome. Like pain, it could be considered an important patient-reported outcome to assess patient satisfaction. The study aims to compare the prevalence of patient-perceived noise of an ultra-congruent total knee prosthesis (Score 2, Amplitude) versus a posterior-stabilized total knee prosthesis (Anatomic, Amplitude).

Participants needed: 170
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: ElsanUpdated: Mar 4, 2026Locations: 1
Eligibility criteria

Adult patients receiving a primary TKA [+3]

History of knee surgery on the concerned/studied knee (except arthroscopic surge... [+5]