Lab Interference

1

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Condition / disease
Location
Status: Not yet recruiting

Effect of Activated Charcoal on Serum Osmolality, Osmolal Gap, and Enzymatic Ethylene Glycol Assay

The goal of this observational study is to determine whether a clinically relevant dose of activated charcoal raises the serum osmolality and osmolal gap in a population of healthy volunteers. Secondarily to determine whether the same dose creates a false positive result using an enzymatic assay. 1. Does a clinically relevant dose of commercially available activated charcoal raise the osmolal gap above the baseline of a healthy volunteer? 2. Does the same dose of charcoal cause a false positive enzymatic assay for ethylene glycol? Participants will be asked to consume a dose of activated charcoal and have serial blood draws for laboratory measurements.

Participants needed: 8
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: State University of New York - Upstate Medical UniversityUpdated: Oct 23, 2025Locations: 1
Eligibility criteria

Healthy adults

Any medical comorbidities [+5]