Mandibular Reconstruction* / Methods

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Review clinical trials related to Mandibular Reconstruction* / Methods. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Patient-specific Reconstruction Plate for Segmental Mandibular Defects

The mandible's horseshoe-shaped anatomy makes the reconstruction of segmental defects a challenging procedure. Conventional reconstruction typically relies on alloplastic plates to bridge bony stumps; however, these require extensive intraoperative bending, often resulting in imperfect adaptation, press-to-contact fixation, and residual stresses that increase the risk of hardware fatigue and fracture. Recent advances in computer-aided design and manufacturing (CAD/CAM) and virtual surgical planning (VSP) have improved precision in maxillofacial reconstruction. Patient-Specific Reconstruction Plates (PSRP), developed from virtual planning and patient-specific anatomical data, offer a bespoke contour adaptation, predictable screw positioning, and elimination of press-fit deformation. This customization improves alignment, mechanical stability, and long-term outcomes.

Participants needed: 14
Trial details
Biological sex: AllType: InterventionalSponsor: Alexandria UniversityUpdated: Jan 6, 2026Locations: 1
Eligibility criteria

Patients with a segmental mandibular continuity defect, not involving the condyl... [+5]

Medically compromised patients contradict the operation. [+3]