Mental Acuity

3

Review clinical trials related to Mental Acuity. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

The Effect of Water Temperature on Heart Rate Variability and Cognition

Heart rate variability (HRV) is a key indicator of fitness, and stress resilience. Previous research has shown that HRV decreases under mental workload, including during tasks that require strict attention. Studies also show that temperature exposure affects attention: cold increases the stress response while warm water has a calming effect. Very few studies combine thermal exposure with cognitive testing, and no controlled trials have investigated whether water temperature modulates HRV responses specifically during cognitive demand.

Participants needed: 30
Trial details
Age: 18-30Biological sex: FemaleType: InterventionalSponsor: Arizona State UniversityUpdated: Jun 17, 2026
Eligibility criteria

Healthy women free of chronic disease (by self-report) [+1]

medication/drug use that has not been consistent for the previous 3 months or wi... [+6]

Status: Not yet recruiting

Effects of Red Panax Ginseng Supplementation on Cognitive Performance and Emotional Well-Being in Young Healthy Adults

College students face substantial and persistent mental health challenges that directly affect cognitive performance, stress regulation, and emotional well-being. Neurological functions such as working memory, attention regulation, executive control, and emotional processing are highly sensitive to stressors, leaving young adults vulnerable to daily fluctuations in cognitive efficiency. Recent findings from the Healthy Minds Network (2025) indicate that although rates of moderate to severe depression among college students declined from 44% in 2022 to 37% in 2025, and anxiety symptoms fell from 37% to 32%, levels of psychological flourishing also dropped, falling to 36% despite these improvements. Ginseng contains bioactive compounds known as ginsenosides that favorably influence brain function and inflammatory cascades. Studies in stressed and moderately stressed adults demonstrated reduced perceived stress, improved emotional processing, enhanced cognitive performance, and beneficial changes to biomarkers with ginseng supplementation. In addition, randomized controlled trials reported improvements in mood regulation, fatigue resistance, and aspects of working memory and attention following short-term ginseng supplementation. This study will examine the effects of daily red panax ginseng supplementation (3000 mg/day; two 1500 mg Red Panax gummies) on cognitive performance and emotional well-being in healthy young adults.

Participants needed: 30
Trial details
Age: 18-30Biological sex: AllType: InterventionalSponsor: Arizona State UniversityUpdated: Jun 16, 2026
Eligibility criteria

Healthy young adults [+1]

medication/drug use that has not been consistent for the previous 3 months or wi... [+10]

Status: Recruiting

Effects of Spirulina Supplementation on Mental Health in Healthy Adults

Spirulina platensis is a form of cyanobacteria, a blue-green algae, and is a superfood most known for being rich in protein, vitamins and minerals, and healthful phytochemicals. Spirulina supports brain health through neuroprotection offered by its antioxidants, anti-inflammatory properties, and hormone regulation. The aim of this study is to supplement healthy adults from a campus community with 3g of spirulina, daily, for 8 weeks to improve mood and mental acuity in comparison to receiving a placebo.

Participants needed: 30
Trial details
Age: 16-65Biological sex: AllType: InterventionalSponsor: Arizona State UniversityUpdated: Aug 19, 2025Locations: 1
Eligibility criteria

healthy adults [+6]

not have been clinically diagnosed with depression [+4]