Metastases, Neoplasm

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Review clinical trials related to Metastases, Neoplasm. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Palliative Dose Escalated Radiation for Painful Non-Spine Bone Metastases and Painful Non-Bone Metas

The investigators hypothesize that with dose escalation to 40-50 Gy in ten fractions, the complete pain response rate at one month can be increased to 40-50% in painful non-spinal bone metastases. Additionally, the investigators hypothesize that utilizing a fractionation scheme with an escalated biologically equivalent dose (BED) will result in a higher proportion of participants responding to treatment, and will also lead to more durable responses. Furthermore, the investigators hypothesize that with dose escalation to 40-50 Gy in ten fractions, the complete pain response rate at one month can be increased to 35-45% in painful non-bone metastases

Participants needed: 124
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Rutgers, The State University of New JerseyUpdated: Jun 2, 2026Locations: 7
Eligibility criteria

Have provided signed informed consent for the trial [+10]

Metastasis from a highly radiosensitive tumor (eg, lymphoma, myeloma, germ cell... [+4]