Metastatic Urothelial Cancer

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Review clinical trials related to Metastatic Urothelial Cancer. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Acupuncture and Exercise for EV-Pembro-Induced Peripheral Neuropathy

The goal of this study is to evaluate the feasibility and preliminary efficacy of a combined acupuncture and exercise intervention for the management of chemotherapy-induced peripheral neuropathy (CIPN) in participants with metastatic bladder cancer receiving enfortumab vedotin (EV) and pembrolizumab (Pembro). The names of the two study groups in this research study are: * Acupuncture + Virtual Exercise (AVE) * Virtual Exercise Only (VE)

Participants needed: 50
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Dana-Farber Cancer InstituteUpdated: May 4, 2026Locations: 1
Eligibility criteria

Age ≥ 18 years old [+10]

History of peripheral neuropathy prior to EV-Pembro initiation [+6]

Status: Recruiting

Study of Sacituzumab Govitecan in Participants With Urothelial Cancer That Cannot Be Removed or Has Spread

The objective of this study is to evaluate the efficacy and safety of sacituzumab govitecan-hziy monotherapy and with novel combinations in participants with metastatic urothelial cancer (mUC).

Participants needed: 827
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Gilead SciencesUpdated: Mar 16, 2026Locations: 135
Eligibility criteria

Female or male individuals, ≥ 18 years of age (19 Years old for South Korea). [+20]

Females who are pregnant or lactating. [+18]

Status: Recruiting

Clofarabine Therapy in Locally Advanced or Metastatic Urothelial Carcinoma

This phase 1/2 study will evaluate the maximum tolerated dose, efficacy, and safety of clofarabine in patients with advanced or metastatic urothelial cancer.

Participants needed: 50
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Ekaterina LaukhtinaUpdated: Jun 26, 2025Locations: 1
Eligibility criteria

Patients with histologically or cytologically confirmed urothelial carcinoma, ra... [+13]

Received previous treatment with clofarabine [+12]