Muscle Tone

4

Review clinical trials related to Muscle Tone. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Foam Roller Compared to Massage on Reducing Calf Muscle Tone in Healthy Subjects

Objective: This study aims to compare the effects of two techniques-foam rolling (FR) and therapeutic massage-on reducing the muscle tone in the calf muscles (gastrocnemius and soleus) of healthy individuals. Methods: A randomized, controlled crossover design was used with 40 healthy participants (aged 18-45). Participants were randomly assigned to either a foam roller or a therapeutic massage group. The interventions were applied to the dominant leg, and muscle tone was measured pre- and post-intervention using a MyotonPro device. The primary outcome was muscle tone (Hz), and secondary outcomes included muscle stiffness (N/m) and elasticity (D \[log\]). Results: The study will assess the effectiveness of each intervention on muscle tone, stiffness, and elasticity. It aims to determine whether foam rolling is as effective or superior to traditional massage in reducing calf muscle tone. Conclusion: This research will contribute to understanding the efficacy of foam rolling as a self-administered technique for muscle tone reduction and its potential application in clinical and athletic settings

Participants needed: 20
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Universidad Europea de MadridUpdated: May 4, 2026
Eligibility criteria

Age: Participants aged between 18 and 45 years. [+3]

Musculoskeletal Conditions: Individuals with any pathologies in the calf muscles... [+5]

Status: Recruiting

Wearable Sensors to Detect Atypical Muscle Activation in Young Infants

The purpose of this study is to see if wearable sensor technology can be used to evaluate muscle activity and/or identify atypical muscle tone in infants up to 48 weeks postmenstrual age (8 weeks corrected age). These sensors are placed on the surface of the skin and record data about a child's body movements and muscle activity.

Participants needed: 40
Trial details
Age: 0-8Biological sex: AllType: ObservationalSponsor: Shirley Ryan AbilityLabUpdated: Mar 25, 2026Locations: 2
Eligibility criteria

Hospitalized in the NICU [+9]

Missing or incomplete limbs (such as from amputation or congenital limb defects)... [+5]

Status: Recruiting

Mandibular Stretching and 4-4-8 Breathing Exercises on Autonomic Nervous System Activity

Mandibular stretching exercises and breathing techniques may influence autonomic nervous system activity, muscle tone, and psychological state. This randomized controlled trial aims to investigate the effects of mandibular stretching exercise and the 4-4-8 breathing exercise on autonomic nervous system activity, muscle tone, and psychological parameters in healthy university students. Participants will be randomly assigned to intervention groups and evaluated before and after the intervention period.

Participants needed: 52
Trial details
Age: 18-30Biological sex: AllType: InterventionalSponsor: Mehin MammadzadaUpdated: Mar 16, 2026Locations: 1
Eligibility criteria

Healthy university students [+3]

History of neurological disorders [+4]

Status: Recruiting

Pure Impact Treatment to Strengthen and Tone Abdomen, Quadriceps and Glutes Muscles

Open-label, non-randomized, prospective, single-center, self-controlled clinical study.

Participants needed: 44
Trial details
Age: 25-60Biological sex: AllType: InterventionalSponsor: Sofwave Medical LTDUpdated: Aug 3, 2025Locations: 1
Eligibility criteria

Male or female subjects ≥ 25 years of age and ≤ 60 years of age. [+6]

Pregnant or planning to become pregnant, having given birth less than 3 months a... [+26]