Status: Not yet recruiting
Using Platelet-rich Fibrin in Regenerative Endodontic Treatment in Mature Permanent Teeth
This study aims to evaluate the antibacterial effects of injectable platelet-rich fibrin (i-PRF) in vitro, and to assess the clinical and radiographic outcomes of using advanced platelet-rich fibrin (A-PRF+) and i-PRF in regenerative endodontic treatment of mature permanent teeth with necrotic pulp. The study will compare the effectiveness of PRF-based treatment with conventional blood clot-based regenerative endodontics.
Participants needed: 57
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of Medicine and Pharmacy at Ho Chi Minh CityUpdated: Sep 25, 2025Locations: 1
Eligibility criteria
The tooth has had previous endodontic treatment. [+9]