Neuromuscular Adaptations

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Review clinical trials related to Neuromuscular Adaptations. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Squat Jump Performance and Chiropractic Ankle Manipulation

The goal of this clinical trial is to learn if chiropractic ankle manipulation can improve squat jump performance. It will also learn about the relationship among chiropractic ankle manipulation, ankle range of motion, and squat jump performance. The main questions it aims to answer are: * Does chiropractic ankle manipulation increase squat jump height? * Is there a relationship among chiropractic ankle manipulation, ankle range of motion, and squat jump performance? Researchers will compare squat jump performance between subjects who receive chiropractic ankle manipulations with control subjects to see if ankle chiropractic manipulation works to improve squat jump performance. Participants will: * Visit the research laboratory for one testing session to measure ankle range of motion and squat jump performance, before and after their randomly assigned intervention arm * Receive either a chiropractic ankle manipulations or rest quietly as the control condition during the testing session.

Participants needed: 60
Trial details
Age: 18-35Biological sex: AllType: InterventionalSponsor: Northeast College of Health SciencesUpdated: Jun 16, 2026Locations: 1
Eligibility criteria

age range from 18 to 35 years old; and [+1]

professional or amateur ranked athlete; [+6]

Status: Recruiting

Postpartum Exercise Intervention

The postpartum period is associated with decreases in physical activity levels, muscular strength, muscular endurance, and pelvic floor muscle function, but little scientific evidence exists on how best to initiate and progress exercise in the postpartum period. This proposal aims to improve habitual physical activity levels, neuromuscular health (i.e., strength, fatigability, symptom burden) and overall wellbeing (i.e., decreased fear of movement, improved sleep quality, improved perception of quality of life) through participation in a weekly exercise program. This study will help to inform postpartum exercise recommendations and is novel as it allows participants to incorporate their children into the exercise routine, thus removing a primary barrier to physical activity/exercise.

Participants needed: 50
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: Carroll UniversityUpdated: May 29, 2026Locations: 1
Eligibility criteria

18 years of age or older [+1]

less than 6 weeks postpartum or not medically appropriate to engage in exercise... [+6]

Status: Not yet recruiting

Comparison of the Effects of Free Weight and Machine-Based Exercises on Muscular Parameters

The aim of our study is to compare and investigate the effects of resistance exercises performed with free weights and those performed using machine systems on muscular parameters and neuromuscular control.

Participants needed: 26
Trial details
Age: 18-30Biological sex: AllType: InterventionalSponsor: Biruni UniversityUpdated: Mar 27, 2026Locations: 1
Eligibility criteria

Being an individual between the ages of 18-30 years [+3]

Having a neurological or cardiopulmonary system problem that prevents exercise. [+4]

Status: Recruiting

Effects of Strength Training on the Plantar Flexors' Properties After Achilles Tendon Rupture

Among the injuries that affect the Achilles tendon, rupture is one of the most frequent. This injury can generate functional, neuromuscular, and tendon deficits that can last for long periods or even be permanent. In the long term (i.e., more than a year after the injury), individuals present functional impairments related to the lower limb, deficits in the capacity to produce muscle force, as well as higher levels of muscle activation (as a compensatory response). Such changes may be due to injury adaptations in the plantar flexor muscles' architecture, which may have shorter, more pennate fibers, leading to reduced muscle thickness. Furthermore, the Achilles tendon may be elongated, with a greater cross-sectional area, presenting lower stiffness and quality (i.e., lower Young's modulus). Strength training can play an important role in recovering from Achilles tendon ruptures, as it promotes functional, neuromuscular, and tendon adaptations that can minimize deficits caused by the injury. However, there is a gap in the literature regarding strength training, as well as the dose vs response relationship, regarding functional, neuromuscular, and tendon adaptations after Achilles tendon rupture. Thus, the aim of the present study is to compare the effects of a strength training program of different intensities on plantar flexors' functional, neuromuscular, and tendon outcomes after Achilles tendon rupture. Men aged between 20 and 50 years old who suffered a total unilateral rupture of the Achilles tendon between one and five years after the rupture will be included in the study, as well as healthy men who did not suffer the rupture (control group). Participants who have suffered an Achilles tendon rupture will undergo a progressive lower limb strength training program twice a week for a total duration of 12 weeks, which will be randomized between two groups: low intensity (G55 - 55% of 1-RM) and moderate intensity (G70 - 70% of 1-RM). The following outcomes will be evaluated: a) Achilles tendon's morphological (length and cross-sectional area), mechanical (force-elongation relationship and stiffness) and material (stress-strain relationship and Young's modulus) properties; b) triceps surae muscles' morphological (architecture \[fascicle length, pennation angle and thickness\] and quality \[measured by echointensity and specific tension\]) properties; c) ankle functionality (maximum height in the heel raise test); d) the plantar flexors' force production capacity (peak and rate of torque development in different joint positions); e) the plantar flexors' muscle voluntary activation; and f) triceps suraes' neuromuscular capacity (i.e., recruitment curves). Assessments will be performed at two times (pre-training; and after 12 weeks of training \[post-12\]) through functional tests, ultrasound techniques, isokinetic dynamometry, electromyography, and percutaneous electrical stimulation. An intraclass correlation coefficient will be used to verify the test-retest reproducibility of ultrasound measurements. The Chi-Square test will be used to compare the level of physical activity (pre-training) between the groups. The results of the intervention will be expressed using descriptive statistics (mean, standard deviation, and standard error). The normality and sphericity of the data will be tested using the Shapiro-Wilk and Mauchly tests, respectively. A generalized estimating equation, followed by Bonferroni post-hoc, will be used to compare the effects of groups (G55 and G70) and times (pre-training, Post-6, and Post-12). A one-way ANOVA, followed by a Bonferroni post-hoc, will be used to compare the control group participants' limbs with the healthy and injured limbs from both intervention groups (G55 and G70) in the Pre and Post-12 times. The effect size will be estimated for each outcome. All statistical analyzes will be performed using SPSS software.

Participants needed: 67
Trial details
Age: 18-64Biological sex: MaleType: InterventionalSponsor: Federal University of Rio Grande do SulUpdated: Jan 30, 2026Locations: 1
Eligibility criteria

Men aged 18 to 64 who have ruptured their Achilles tendon unilaterally no more t... [+1]

Non-surgical treatment for Achilles tendon rupture; [+6]