Neuromuscular Control

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Review clinical trials related to Neuromuscular Control. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Comparative Effect of Combined Strength, Core and Balance Training on Kinesiophobia, Ankle Instability, Functional Outcomes, and Performance in Table Tennis Players With Functional Ankle Instability

This randomized controlled trial investigates the comparative effect of combined strength and balance training versus balance and core training on kinesiophobia (fear of movement), ankle instability, functional outcomes, and athletic performance in adolescent table tennis players with functional ankle instability (FAI). Participants will be randomly allocated into two groups over a 6-week intervention (3 sessions/week). The Experimental Group will receive combined strength and balance training, while the Control Group will receive balance and core training. Outcomes will be measured using validated tools: TSK-17, CAIT, FAAM, Y-Balance Test, Single-Leg Hop Test, T-Test, and Illinois Agility Test.

Participants needed: 51
Trial details
Age: 15-30Biological sex: AllType: InterventionalSponsor: Ibadat International University, IslamabadUpdated: Jun 26, 2026
Eligibility criteria

Male/female table tennis players aged 15-30 years [+3]

History of ankle fracture or surgery [+3]

Status: Recruiting

Impact of Neuromuscular Control With and Without Electrical Stimulation and Long-term Effect of Kinetic Chain Exercises in Multidirectional Shoulder Instability Patients

Background: Shoulder instability is commonly observed in adolescents and young females, ranging from asymptomatic multidirectional instability (MDI) to symptomatic conditions. Patients with MDI often experience shoulder pain, muscle tension, and episodes of subluxation. This condition is associated with hypermobility spectrum disorder (HSD) and hypermobile Ehlers-Danlos syndrome (hEDS), both characterized by generalized joint laxity and recurrent joint dislocations, significantly affecting daily activities and athletic performance. Current literature lacks clarity on the actual humeral head displacement, shoulder joint kinetics, and muscle activity characteristics during movement in patients with MDI accompanied by HSD or hEDS. Additionally, the effects of electrical stimulation on different shoulder muscles and its impact on humeral head displacement in MDI patients remain to be validated. Objective: The purposes of this study are to (1) examine whether patients with hEDS/HSD and MDI have increased humeral head translation compared to healthy controls during three isometric contraction ; (2) investigate the relationship between humeral head translation and associated muscle activity during three isometric exercises ; (3) examine the effect of NMES and NMCT to humerus/scapula muscles on humeral head translations in MDI patients with hEDS/HSD Outcome measurements: The primary outcomes include changes in acromiohumeral distance (AHD) or humeroglenoid distance (HGD) under four conditions (no stimulation, NMCT, BLH/Infraspinatus/MD stimulation, and SA stimulation) during three isometric contractions (shoulder flexion, horizontal adduction, and fully extended elbow holding weight). The secondary outcomes assess muscle activation differences in BLH, infraspinatus, MD, UT, LT, and SA before and after NMCT.

Participants needed: 60
Trial details
Age: 20-50Biological sex: AllType: InterventionalSponsor: National Taiwan University HospitalUpdated: May 28, 2026Locations: 1
Eligibility criteria

Age: Between 20 and 50 years old.

Shoulder pain caused by trauma. History of shoulder fractures or dislocations. C...

Status: Not yet recruiting

Structured Neuromuscular Exercise Program

This randomized controlled trial aims to investigate the effects of an 8-week structured neuromuscular exercise program on running performance and lower extremity biomechanics in recreational runners. The program includes progressive exercises focusing on hip and core strength, balance, plyometric control, and running-specific mobility. Participants will be randomly assigned to an intervention or control group. The intervention group will perform the neuromuscular training twice a week for eight weeks, while the control group will not receive any structured exercise. Pre- and post-intervention assessments will include biomechanical analysis and functional performance tests. The study aims to provide evidence for the preventive and performance-enhancing benefits of neuromuscular training in runners.

Participants needed: 24
Trial details
Age: 18-55Biological sex: AllType: InterventionalSponsor: Elif TunçUpdated: May 19, 2026Locations: 1
Eligibility criteria

Age between 18 and 55 years

History of lower limb surgery or fracture in the past 6 months

Status: Recruiting

Study of Functional Magnetic Resonance Signal Variations in Patients Undergoing Anterior Cruciate Ligament Reconstruction With the Application of a Dedicated Neuromotor Training

Lower limb injuries represent the majority of sports-related injuries, with knee injuries being among the most common. In particular, anterior cruciate ligament (ACL) injuries are considered highly devastating and career-threatening for both professional and amateur athletes. Current surgical and rehabilitation treatments often fail to provide fully satisfactory short- and long-term outcomes. A very high risk of re-injury exists, especially in younger patients, with up to 35% experiencing a second ACL injury, alongside a significant long-term risk of early knee osteoarthritis. Most ACL injuries are non-contact or indirect contact injuries, implicating biomechanical factors and neuromuscular control as key determinants of injury mechanisms. Recent literature shows that patients suffering a non-contact ACL injury have a higher risk of re-injury compared to those with contact injuries, suggesting a significant cognitive component in injury processing, surgery, rehabilitation, and return to sport. Recent rehabilitation studies have introduced targeted neuromotor training designed to "rebuild" biomechanical and neuromuscular patterns to avoid mechanisms leading to re-injury. Movement quality tests are used post-training to confirm the reduction of risky biomechanical patterns, often resulting in a score indicating movement quality. Given the brain's involvement in such injuries, pioneering studies have used functional magnetic resonance imaging (fMRI) to investigate changes in cortical brain areas following ACL injury and reconstruction. Evidence shows adaptations in both central and peripheral nervous systems, with altered sensorimotor cortex activation in patients during simple motor tasks, differing from healthy subjects. Prefrontal cortex alterations correlate with severe quadriceps muscle activation asymmetries, linking these brain patterns to post-injury return-to-sport outcomes. However, no studies have yet evaluated the interaction between cortical activation (neural compensations) measured by fMRI and outcomes from targeted neuromotor training during ACL rehabilitation. Understanding brain activation implications is crucial for developing large-scale rehabilitation protocols to reduce the risk of a second, potentially more devastating, knee injury. This study aims to reveal whether a neuromotor training protocol can positively influence cognitive brain areas related to human movement, particularly by reducing risky injury patterns. It will be the first to test whether dedicated neuromuscular training effectively reduces neural compensations and cortical activation related to non-automated movement, favoring automation areas important for a safe return to sport. Patients will directly benefit from participating in the innovative neuromotor training program, with functional MRI scans conducted before training begins (post-surgery) and after training completion. Indirectly, the study will assess whether neuromotor training can adapt patient neuromotor patterns to reduce re-injury risk, ultimately benefiting future patients undergoing ACL reconstruction.

Participants needed: 12
Trial details
Age: 18-30Biological sex: AllType: InterventionalSponsor: Stefano ZaffagniniUpdated: Feb 27, 2026Locations: 1
Eligibility criteria

Patients who have undergone anterior cruciate ligament reconstruction surgery at... [+4]

History and/or evidence of any neurological disorder or functional impairment; [+6]