Opioid Sparing Anaesthesia

1

Review clinical trials related to Opioid Sparing Anaesthesia. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Effect of Opioid-sparing Anesthesia on Quality of Recovery After Emergency Laparotomy

Opioids are widely used during anesthesia for pain control, but they cause many side effects-such as nausea, constipation, respiratory depression, dependence, and delayed recovery. They can also worsen low blood pressure in patients with unstable circulation. Because of these risks, multimodal analgesia is recommended to reduce opioid use. Research on other non-opioid options is limited. Systemic lidocaine offers anti-inflammatory and opioid-sparing benefits and improves recovery in elective colorectal surgery, but its role in emergency laparotomy is still unclear and requires further study.

Participants needed: 120
Trial details
Age: 21-65Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Dec 3, 2025Locations: 1
Eligibility criteria

Adult patients (21-65 years), ASA I-III undergoing emergency laparotomy with mid...

Severe cardiac morbidities (impaired contractility with ejection fraction < 45%,... [+5]