Status: Not yet recruiting
Effect of Metformin Iontophoresis on Knee Osteoarthritis in Postmenopausal Women
This study is designed as a randomized, double-blind, placebo-controlled clinical trial with two parallel groups. All participants will receive a standardized physical therapy rehabilitation program. Participants will be randomly allocated into either a study group receiving metformin iontophoresis or a control group receiving placebo iontophoresis. Both participants and outcome assessors will be blinded to group allocation.
Participants needed: 68
Trial details
Phase: Phase 3Age: 50-70Biological sex: FemaleType: InterventionalSponsor: Badr UniversityUpdated: Feb 9, 2026Locations: 1
Eligibility criteria
• Postmenopausal women aged 50-70 years. [+7]
• Severe knee osteoarthritis (Kellgren-Lawrence grade IV). [+9]