Partial Edentulism

7

Review clinical trials related to Partial Edentulism. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Intraoral vs Extraoral Cementation of Zirconia Bridges on Ti-Bases: Microstrain Evaluation

This prospective clinical study compares two cementation techniques for implant-supported zirconia fixed partial dentures on titanium bases (Ti-bases): extraoral cementation performed on the working model and intraoral cementation performed chairside. Thirty clinical cases with two osseointegrated implants requiring a multi-unit zirconia restoration will be recruited at the UIC Dental Clinic. For each case, two restorations with identical design will be produced: one will be cemented extraorally (control) and an identical replica will be cemented intraorally (test). Micro-deformation will be assessed as peri-implant microstrain (µε) using a standardized strain-gauge setup and the same recording protocol for both techniques. The primary analysis compares microstrain between intraoral and extraoral cementation within each case; implant/prosthetic events will be recorded descriptively.

Participants needed: 30
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Universitat Internacional de CatalunyaUpdated: Mar 4, 2026Locations: 1
Eligibility criteria

Adults (≥18 years old) in good general health. [+4]

ASA III or ASA IV. [+5]

Status: Recruiting

In Vivo Evaluation of the Accuracy of Immediate Screw-Retained Provisional Crowns Fabricated Using Digital Planning and Guided Surgery

This clinical trial aims to evaluate the in vivo accuracy of a fully digital workflow for the immediate placement of a previously fabricated screw-retained provisional crown using digital planning and guided implant surgery. The study will be conducted in partially edentulous adult patients requiring the replacement of a single tooth with an immediately loaded dental implant. The main objective of the study is to assess the accuracy (trueness and precision) of the planned digital implant position and provisional restoration by comparing the virtually planned position with the actual clinical outcome after guided surgery. Emphasis will be placed on linear, angular, and rotational deviations at both the implant and provisional restoration levels. Participants will undergo a fully guided implant placement procedure with rotational control, followed by the immediate placement of a prefabricated screw-retained provisional crown designed during the digital planning phase. Postoperative intraoral scans will be obtained to register the final implant and restoration positions. The planned and achieved positions will be compared using three-dimensional analysis software to quantify deviations and determine whether the accuracy achieved remains within clinically acceptable limits.

Participants needed: 27
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Universidad Complutense de MadridUpdated: Jan 9, 2026Locations: 1
Eligibility criteria

Adults aged 18 years or older. [+5]

Patients classified as ASA III or ASA IV, or with uncontrolled systemic conditio... [+3]

Status: Not yet recruiting

Prospective Study of Bone Augmentation With Lateral Sinus Lift and Osseointegration of Dental Implants

By using a split-mouth model in the maxilla, lateral sinus lift procedures will be performed using xenograft on one side vs autologous bone augmentation and PRF membranes on the other side. The purpose is to qualify and verify each step of this study to ensure the reliability and validity of the results.

Participants needed: 20
Trial details
Age: 18-100Biological sex: AllType: InterventionalSponsor: Maria H. PhamUpdated: Jun 24, 2025
Eligibility criteria

Partially edentulous jaws in the lateral segment with 2 or more nearby lost teet... [+2]

ASA group 3 and above [+9]

Status: Recruiting

Extra-short vs. Non-extra-short Dental Implants Splinted on the Same Prosthesis

The main aim of this prospective study is to analyze the survival rate of short-length implants (\<6.5 mm) in subjects with partial edentulism. Non-short length implant will be used as control arm. Additionally, others clinical parameters (marginal bone loss and prosthetic associated complications) will be measured.

Participants needed: 102
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Fundación Eduardo AnituaUpdated: Apr 17, 2025Locations: 1
Eligibility criteria

Age ≥ 18 years [+5]

Smokers> 10 cigarettes / day [+2]

Status: Not yet recruiting

Surgical Guided Fabricated From Two Different Printing Materials

implant will be inserted in patients with kennedy class 3 or 4 partially edentulous mandible .the implants will be inserted using teeth supported surgical guide fabricated from two different materials

Participants needed: 12
Trial details
Age: 21+Biological sex: AllType: InterventionalSponsor: Suez Canal UniversityUpdated: Oct 8, 2024
Eligibility criteria

Patients with skeletal Angle´s class I maxilla-mandibular relationship, [+3]

Smokers. [+3]

Status: Recruiting

A Smart Digital Workflow Towards High Precision and Through-Put Production for Removable Partial Dentures

Tooth loss is a major chronic problem in dentistry and edentulous elderly endures poorer quality of life worldwide. Removable partial dentures (RPDs) are the most widely accepted and cost-effective treatment for patients to restore oral functions. RPDs contain three components including the metal framework, denture base and acrylic teeth. Conventionally, RPD fabrication involves tedious clinical and dental laboratory procedures and is time consuming, labour-intensive, and often imprecise, therefore incapable of meeting the growing demands of RPD by an ageing population. The challenges to achieve a high quality and high-throughput RPD service lie in three aspects: 1) accuracy in capturing oral profile; 2) immediate oral information analysis and device design, and 3) automation in production.

Participants needed: 141
Trial details
Age: 21+Biological sex: AllType: InterventionalSponsor: National Dental Centre, SingaporeUpdated: Aug 9, 2024Locations: 1
Eligibility criteria

above the age of 21 years' old [+4]

History of maladaptation to denture use [+2]

Status: Recruiting

Clinical Performance of Long-span Fixed Partial Dentures

Tooth-coloured fixed restorations are becoming increasingly popular with patients and dentists. If high-strength all-ceramics such as zirconia are used as the restoration material, a maximum of two adjacent missing teeth can be replaced with the aid of fixed partial dentures (FPDs). For the replacement of a missing anterior or posterior tooth by FPDs, a very good clinical performance similar to that of metal-based, ceramic-veneered restorations can be expected. However, evidence-based statements on the clinical performance of long-span all-ceramic FPDs are difficult because there are only very few studies on this topic, which are also inhomogeneous with regard to the study conditions. Randomized studies to compare monolithic (consisting only of the high-strength framework material) or partially veneered (weaker veneering ceramics in esthetically relevant tooth areas) all-ceramic and classic (completely veneered) metal-ceramic FPDs are lacking. The aim of the current explorative, prospective, randomized, two-arm clinical interventional study is therefore to compare the clinical performance of long-span FPDs (≥ 4 Pontics) made of monolithic / facially veneered zirconium dioxide with a gold standard (completely veneered cobalt chromium (CoCr)-based FPDs). Forty patients will be recruited. Once all inclusion criteria have been established, including the signed informed consent of the patients informed of the content, effort, advantages and disadvantages of the study, patients are assigned to the two study groups by stratified block randomization (main strata: tooth-supported / (tooth-)implant-supported). After placement of the restorations, follow-up examinations are performed after 1 week (baseline) and after half a year, one year, two years and three years. In addition to the main target criterion (veneering defects), further complications (related to FPDs or supporting tissues / structures) and parameters of oral health are recorded. Depending on the distribution and structure of the data, parametric and non-parametric statistics are used. Group differences with respect to the main target criterion ceramic defects are to be investigated by log-rank and chi-square tests. The significance level is set at α \< 0.05. Since this is an explorative study, all p-values are descriptive.

Participants needed: 40
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University Hospital HeidelbergUpdated: May 9, 2023Locations: 1
Eligibility criteria

The patient is at least 18 years old. [+4]

Pregnancy and lactation [+13]