Patient Preference

8

Review clinical trials related to Patient Preference. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Tradeoffs in Patient Decision Making About Rectal Cancer Treatment: Benefits Compared to Quality Of Life.

This study is aiming to look into patients' treatment preferences and their socio economic background as well as the exploration of thought processes leading to these preferences. It will integrate, in two exploratory questionnaires, the three most common treatment schema (standard of care, non-operative management, surgery alone) all of which have been demonstrated efficacious.

Participants needed: 192
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Sir Mortimer B. Davis - Jewish General HospitalUpdated: May 14, 2026Locations: 1Duration: 3 Weeks
Eligibility criteria

New rectal cancer patient [+7]

Patient unable to sign a consent form [+6]

Status: Recruiting

Eliciting Informed Goals of Care in Elderly Patients

Patient-centered medical care considers a patient's values and goals for their health and well-being. Healthcare providers use this information to formulate a medical care plan that is aligned with these expectations. This shared-decision making process should occur with every medical decision, but it is especially important whenever decisions about end-of-life care are being considered. Eliciting patient preferences about resuscitation and life-support treatments in the event of life-threatening illnesses are considered to be a standard of excellent and appropriate medical care. Unfortunately, these discussions don't happen consistently and even when they do occur, are rarely ideal. The consequences can be devastating, often resulting in the delivery of unwanted medical care that can be associated with significant physical and mental suffering among patients and their families. In response to this problem, the investigators developed a novel tool to help guide these difficult conversations between healthcare providers and patients. The investigators previously tested this tool in a small group of hospitalized patients who found it acceptable and helpful. In this larger study, the investigators will compare how effective this tool is compared to usual care in ensuring hospitalized patients have their treatment preferences identified, documented and result in end-of-life care that is consistent with their preferences.

Participants needed: 1,200
Trial details
Age: 80+Biological sex: AllType: InterventionalSponsor: Royal Victoria Hospital, CanadaUpdated: Nov 21, 2025Locations: 1
Eligibility criteria

Hospitalized patients ≥ 80 years old with an acute medical or surgical condition... [+4]

Treating physician, patient, or substitute decision maker declines [+5]

Status: Not yet recruiting

The VIP3 (Very Old Intensive Care Patients) Study: Family Involvement in Treatment Decisions for Old ICU Patients

The demographics of the global population is changing with increasing numbers of elderly and co-morbid patients. As a result, more elderly patients will be admitted to the Intensive Care Unit (ICU), which will bring several ethical challenges. It is for this reason the investigators have chosen to focus on this historically neglected and important patient population. Little is known about how family meetings are implemented in ICUs in Europe and other parts of the world. However, these meetings contribute to building trust between the family and the ICU team. They are a crucial component for planning and conducting a time limited trials as they provide the opportunity for shared-decision making with the ICU team and with other stakeholders. The investigators plan to determine the current practice of communication between ICU staff and patients and their relatives. The investigators expect to find a substantial variation in approaches to family meetings. This information may then help design and further investigate targeted interventions enabling shared decision-making focused on family and patient values. The investigators research aim is to to investigate whether Family meetings are used in ICUs across Europe and other regions and, if so, how they are conducted and the influence on patient-centred outcome measures.

Participants needed: 2,000
Trial details
Age: 75+Biological sex: AllType: ObservationalSponsor: St George's, University of LondonUpdated: Jun 25, 2025
Eligibility criteria

Patients admitted to the Intensive Care Unit (ICU) of participating centres [+2]

Refusal to participate [+2]

Status: Recruiting

TENS Unit for Analgesia During IUD Insertion

Subjects will be screened over the phone or in Tufts GYN clinic for participation in the study. If eligible and interested in participating, written informed consent (and assent if applicable) will be obtained. After informed consent/assent, the patient will be enrolled in the study. The patient will decide if they desire to use TENS unit during IUD insertion appointment and inform the study team. The clinic visit will proceed as normal, with additional study proceedings as follows. The study personnel will complete the 'Background Questionnaire' with the patient prior to IUD insertion. During the IUD insertion appointment, study personnel will assist in collection of the 'Study visit' data collection form. This includes recording the patient's pain score at various time points throughout the insertion procedure: * anticipated pain during IUD insertion * baseline pain prior to insertion * speculum insertion * tenaculum placement * paracervical block administration (if performed) * cervical dilation (if performed) * uterine sounding * IUD insertion * 5 minutes after IUD insertion Study personnel will also time the insertion procedure and collect additional data as outlined in the 'Study visit data collection form.' After IUD insertion, the participant will be asked to complete the 'Post-IUD Insertion Survey.' Once this survey is complete, this will conclude the study participation. Participation will last through the study visit only. As part of the standard of care, a urine pregnancy test will be obtained and confirmed negative prior to IUD insertion. Patients will receive routine pain management modalities per shared decision-making with their clinical provider which may include NSAID administration, paracervical block, and heating pad.

Participants needed: 40
Trial details
Age: 12-50Biological sex: FemaleType: InterventionalSponsor: Tufts Medical CenterUpdated: Jun 4, 2025Locations: 1
Eligibility criteria

Persons with a uterus desiring insertion of intrauterine device [+3]

Unable to provide informed consent/assent [+13]

Status: Recruiting

CT-Angiography Plaque Characteristics and Events in Deferral Patients by Invasive Fractional Flow Reserve

Fractional flow reserve (FFR)-guided PCI for chronic coronary syndromes (CCS) is reported to improve the outcomes compared with angiography-guided PCI. However, cardiac-events still occur in FFR-deferral patients in long-term follow-up. Coronary computed tomography angiography (CTA)-defined high-risk-plaque (HRP) is known to relate future cardiac events. The investigators hypothesized that CTA might identify plaque features linked to future cardiac events in deferral patients.

Participants needed: 400
Trial details
Age: 20+Biological sex: AllType: ObservationalSponsor: Fujita Health UniversityUpdated: Jan 3, 2025Locations: 1Duration: 3 Years
Eligibility criteria

men and women aged ≥20 years, [+2]

patients with a history of coronary bypass grafting (CABG) because CABG changed... [+2]

Status: Not yet recruiting

Switch From Oral Therapy to Long-acting Injectable Cabotegravir + Rilpivirine

This protocol will assess the level of satisfaction, acceptance of treatment and quality of life of patients with undetectable HIV who voluntarily change from oral to injectable antiretroviral treatment at 72 weeks of follow-up.

Participants needed: 50
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Pontificia Universidad Catolica de ChileUpdated: Nov 7, 2024Locations: 1
Eligibility criteria

HIV-1 positive patients, on antiretroviral therapy [+3]

Previous virological failure [+5]

Status: Recruiting

The PRIME Study: A Randomized, Controlled, Prospective Study

To investigate the outcomes of patients undergoing bilateral RLE surgery with treatment of dexamethasone intracanilicular insert compared to topical standard care steroid. Desiged to look at patient preference comparing the insert to drops and will also look at patient outcomes including inflammatin and risk of cystoid macular edema post-operatively.

Participants needed: 20
Trial details
Phase: Phase 4Age: 22-75Biological sex: AllType: InterventionalSponsor: Vance Thompson Vision - MTUpdated: Sep 16, 2020Locations: 1
Eligibility criteria

Any adult patient who is planned to undergo bilateral RLE surgery with BCVA 20/3... [+2]

Patients under the age of 22 or above the age of 75 [+10]

Status: Recruiting

A Trial Evaluating Patient Preference of Dropless vs Drops Post Cataract Surgery

To evaluate the safety and ocular efficacy of Dextenza in combination with an intracameral antibiotic and NSAID in controlling post-operative ocular pain and inflammation compared to standard of care topical therapy in patients undergoing bilateral cataract surgery.

Participants needed: 50
Trial details
Phase: Phase 4Age: 22-100Biological sex: AllType: InterventionalSponsor: Ophthalmic Consultants of Long IslandUpdated: Dec 20, 2019Locations: 1
Eligibility criteria

A male or female subject in good general health (as determined by the Investigat... [+4]

A subject with a history of complications, adverse events, trauma or disease in... [+36]