Perioperative Opioid Sparing Techniques

1

Review clinical trials related to Perioperative Opioid Sparing Techniques. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Efficacy of Perioperative Opioid Sparing Techniques on Time to Initiation of Chemotherapy

The primary purpose of this study is to determine if intrathecal morphine (ITM) administration is superior to quadratus lumborum block or surgeon administered transversus abdominis plane (TAP) blocks result in decreased time to initiation of chemotherapy following oncologic surgery. The secondary objectives of this study are to determine: * The difference between interventions in time to return of bowel function in days * The difference between interventions in incidence of opioid related adverse drug events (ORADEs) * The difference between interventions in cumulative and post-operative total morphine milligram equivalents * The difference between interventions in quality-of-life assessment tool and patient satisfaction (brief pain index short form BPI-sf9) * The difference between interventions in hospital length of stay in days * The difference between cumulative pain scores between interventions * The difference between short acting and long-acting bupivacaine in pain management and time to chemotherapy The hypothesis is that preoperative intrathecal morphine administration will significantly reduce the time to initiation of postoperative chemotherapy.

Participants needed: 200
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: University of Tennessee Graduate School of MedicineUpdated: Sep 4, 2025Locations: 1
Eligibility criteria

18-80 years of age [+8]

Chronic Opioid Use (received an opioid within 90 days preoperatively) [+15]