Persistent Tic Disorder

2

Review clinical trials related to Persistent Tic Disorder. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Remote Delivery of a Mindfulness-based Intervention for Tics

This research study is being done to compare a mindfulness-based intervention for tics (MBIT) to psychoeducation with relaxation and supportive therapy (PRST) for individuals with Tourette's syndrome or Persistent Tic Disorders (collectively TS). It is the investigator's hope that this information cam be used to improve current treatments for individuals with TS.

Participants needed: 150
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Johns Hopkins UniversityUpdated: May 11, 2026Locations: 1
Eligibility criteria

be ≥18 years of age; [+6]

a current diagnosis of substance use disorder, psychosis, mania or another condi... [+3]

Status: Recruiting

Multimodal Profiling of Response to Pediatric Comprehensive Behavioral Intervention for Tics

Tourette Syndrome and Persistent Motor/Vocal Tic Disorder affect 1-3% of youth and can be associated with impaired functioning, emotional and behavioral problems, physical pain, diminished quality of life, and peer victimization. Chronic tics are the primary symptom. Comprehensive Behavioral Intervention for Tics (CBIT) is a manualized treatment focused on tic management skills. During the core CBIT procedure, competing response training, patients learn to inhibit tics by engaging in a competing motor action. The overall objective of this study is to identify bio-behavioral predictors and correlates of response and the most potent aspects of CBIT. Participants with chronic tics will complete a manualized course of 8-session CBIT. Neural, behavioral, psychosocial, and global functioning will be assessed longitudinally to examine predictors and correlates of response. CBIT sessions will be video recorded. CBIT process will be measured with a video-based behavioral coding scheme that will be refined and validated during years 1-2 using archival CBIT videos

Participants needed: 100
Trial details
Phase: Phase 2Age: 10-17Biological sex: AllType: InterventionalSponsor: University of MinnesotaUpdated: Jul 14, 2025Locations: 2
Eligibility criteria

Age 10-17 years at time of enrollment. [+5]

Inability to undergo MRI (e.g., metal in body, claustrophobia, orthodontia) and/... [+7]