Status: Recruiting
Neuroprotection Bundles For Comatose Survivors Following Cardiac Arrest
The investigators designed LAPTOPS to determine the effectiveness of a goal-directed neuroprotection bundles of active management including body temperature,PaCO2,PaO2,position,Blood glucose ,blood sodium,Blood pressure and Lactate vs. usual care in adult post-cardiac arrest care. LAPTOPS is a large-scale pragmatic clinical trial to provide reliable evidence over the effectiveness of a widely applicable goal-directed care bundle in acute phase of adult post-cardiac arrest care.
Participants needed: 1,008
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Xiangya Hospital of Central South UniversityUpdated: Nov 18, 2025Locations: 1
Eligibility criteria
Age ≥ 18 years and < 80 years [+3]
Unwitnessed cardiac arrest, estimated time from cardiac arrest to start of CPR >... [+6]