Post-Operative Complications

9

Review clinical trials related to Post-Operative Complications. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Swedish National Parotidectomy Study (SNaPs): Drainless Versus Standard Surgery

The purpose of this study The purpose of this study is to find out if it is safe to perform surgery on the parotid gland (the large salivary gland in front of the ear) without using a wound drain. A wound drain is a small plastic tube used to remove excess fluid from the surgical site after the operation. Currently, using a drain is the standard practice in Sweden, which often means patients must stay in hospital overnight. Researchers want to see if skipping the drain is just as safe and if it could allow more patients to return home on the same day as their surgery. What happens during the study Participants in this study will be randomly assigned to one of two groups during their surgery: Group 1: Will receive the standard treatment with a wound drain. Group 2: Will have the surgery performed without a wound drain. Apart from the use of a drain, all participants will receive the same surgical care. After the operation, researchers will monitor the healing process. Participants will be asked to fill out questionnaires about their health and any symptoms at one week and six months after their surgery. The goal of the study The main goal is to compare the safety of the two methods. Researchers will look at whether there is any difference in the number of complications, such as fluid build-up (seroma), bleeding, or infections, between those who had a drain and those who did not. The study also aims to evaluate if avoiding a drain improves the patient's quality of life and if it is a more cost-effective approach for the healthcare system.

Participants needed: 600
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Uppsala University HospitalUpdated: Jun 4, 2026Locations: 3
Eligibility criteria

Patients scheduled to undergo partial or superficial parotidectomy without concu... [+3]

Previous parotid surgery on the same side [+11]

Status: Not yet recruiting

Vascular Events in Noncardiac Surgery Patients Cohort Evaluation Study 2

VISION-2 is an international, multi-site, prospective observational cohort study of 20,000 patients undergoing noncardiac surgery. Continuous biometric data will be blindly collected for the first 30 postoperative days, in hospital and at home, using Vitaliti™. Following study enrollment and baseline data collection, follow up visits will occur in-hospital, at 30-days, and 1-year post-operatively. VISION-2 has 3 primary objectives, among participants who underwent noncardiac surgery, the investigators will: 1) determine the pattern and frequency of physiological precursors (i.e., biophysical signals) to MINS, BIMS, sepsis, and infection without sepsis; 2) build prediction models from these biophysical signals and their extracted features through supervised machine learning, for the prediction and early detection of those complications; and 3) build a biobank for evaluation of novel biomarkers.

Participants needed: 20,000
Trial details
Age: 65+Biological sex: AllType: ObservationalSponsor: Hamilton Health Sciences CorporationUpdated: Apr 14, 2026Locations: 3
Eligibility criteria

age ≥65 years; [+2]

hearing aid(s) or cochlear implant(s) in left ear; [+6]

Status: Recruiting

Continuous Vital Sign Monitoring Versus Routine Spot-checks in Patients After Non-cardiac Surgery

The "COME ON, NOW!" trial is a randomized, single-center trial in patients recovering from non-cardiac surgery on normal wards investigating whether continuous vital sign monitoring - compared to routine spot-checks by nurses - reduces the total duration of abnormal vital signs per hour during the first 48 hours after admission to the normal ward.

Participants needed: 264
Trial details
Age: 45+Biological sex: AllType: InterventionalSponsor: Universitätsklinikum Hamburg-EppendorfUpdated: Mar 2, 2026Locations: 1
Eligibility criteria

Emergency surgery [+4]

Status: Recruiting

Prevention of Edema After Coronary Artery Bypass Graft by Customized Pressure-guided Elastic Bandages

The study aimed to assess the efficacy of customized pressure-guided elastic bandages (CPG-EB) in preventing postoperative edema and complications in Coronary Artery Bypass Graft (CABG) patients. While compression therapy, like compressive stockings, has benefits in preventing edema, concerns about affordability persist. CPG-EB provides optimal sub-bandage pressure, proven effective in venous leg ulcers. Implementing CPG-EB post-CABG could enhance venous blood flow, reducing complications and improving outcomes. Patients were divided into two groups: one with CPG-EB and the other standard post-CABG care. Data collected at 1, 2, and 6 weeks post-surgery assessed swelling and wound complications. Comparative analysis used standardized criteria.

Participants needed: 106
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Siriraj HospitalUpdated: Feb 9, 2026Locations: 2
Eligibility criteria

All patients scheduled for elective coronary artery bypass grafting (CABG) surge... [+1]

Patients with an Ankle-brachial pressure index (ABI) < 0.8 [+2]

Status: Recruiting

Frailty and Muscle Strength Tests in Older Adults Undergoing Major Surgery

The goal of this observational study is to learn if simple tests for frailty and muscle strength can help predict which older adults (age 65 and older) are at higher risk for problems after major abdominal surgery. The main questions it aims to answer are: * Do measures of frailty and muscle strength, taken before surgery, predict complications after surgery? * Can these tests be easily done during a routine pre-surgical visit? Participants will: * Complete brief tests measuring muscle strength, breathing strength, physical function, nutrition status, body composition, and memory during a regular pre-surgical clinic appointment. * Allow researchers to review their medical records 30 and 90 days after surgery to identify any complications or health problems.

Participants needed: 100
Trial details
Age: 65+Biological sex: AllType: ObservationalSponsor: University of North Carolina, Chapel HillUpdated: Jan 28, 2026Locations: 1
Eligibility criteria

Age 65 years or older. [+3]

Surgery is an emergency procedure. [+2]

Status: Recruiting

Enhanced Vitals Monitoring After Major Surgery Trial

The aim of this clinical trial is to examine the feasibility of an enhanced vital sign monitoring solution in-hospital and at-home. This study includes adult patients undergoing inpatient major vascular or abdominal surgery. Researchers will compare the enhanced vitals monitoring group to the standard of care group to see if it may change post-operative management and outcomes. The primary question it aims to answer is if enhanced monitoring of surgical patient vitals can increase the number of days at home alive in the first 30 days after surgery. Participants in the intervention group will test two vitals monitoring devices, one in the hospital and one at home. They will also be asked to complete several questionnaires and a follow up phone call.

Participants needed: 110
Trial details
Age: 19+Biological sex: AllType: InterventionalSponsor: University of British ColumbiaUpdated: Nov 21, 2025Locations: 2
Eligibility criteria

Undergoing inpatient major abdominal (general surgery, urology, or gynecology) o... [+3]

Patient refusal [+8]

Status: Not yet recruiting

Evaluation of Cranial Flap Fixation With Montage Flowable Settable Bone Paste

Montage Flowable Settable Bone Paste is a self-setting calcium phosphate cement indicated for use in the repair of neurosurgical burr holes, contiguous craniotomy cuts and other cranial defects with a surface area no larger than 25cm2. It is also intended to be used for the fixation of cranial bone flaps following craniotomy. The MONTAGE Flowable device comprises two separate components of paste-like consistency containing granular calcium phosphate, calcium stearate, vitamin E acetate, a triglyceride, polyalcohols and a mixture of a lactide-diester and polyester-based polymers. When mixed together in the applicator tip, the components of the MONTAGE Flowable device form a cohesive paste-like material that adheres to the bone surface and remains in place following application. The resulting hardened, resorbable material is primarily calcium phosphate. The components must be mixed immediately prior to use.

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Abyrx, Inc.Updated: Aug 5, 2025
Eligibility criteria

Male or female > 18 years of age [+2]

Subject requires a procedure involving a translabyrinthine, transsphenoidal, tra... [+10]

Status: Not yet recruiting

Reducing Deaths After Surgery in Low- and Middle-income Countries: A Pilot Cluster Randomised Trial

SurgPASS is a pilot randomised cluster trial utilising a pre-operative checklist with the aim of reducing deaths after surgery. If SurgPASS is successful, the intervention will be implemented in a separate full-scale cluster randomised trial.

Participants needed: 300
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of BirminghamUpdated: Apr 17, 2025Locations: 5
Eligibility criteria

Patients undergoing emergency major abdominal surgery (i.e., midline or non-midl... [+2]

Minimally invasive surgery [+1]

Status: Recruiting

Web-based International Register of Emergency Surgery and Trauma

The WIRES-T project (Web-based International Registry of Emergency General Surgery and Trauma) has been set up to allow to all the EGS (Emergency General Surgery) and Trauma surgeons to register their activity and to obtain a worldwide register of traumatic and non traumatic surgical emergencies. This will give the opportunity to evaluate results on a macro-data basis and to give index allowing stratifying, evaluating and improving the outcomes.

Participants needed: 10,000
Trial details
Biological sex: AllType: ObservationalSponsor: A.O. Ospedale Papa Giovanni XXIIIUpdated: Jul 14, 2020Locations: 1Duration: 2 Weeks
Eligibility criteria

Patients affected by an acute surgical disease [+2]

Patients not affected by an acute surgical disease [+1]