Refractory Status Epilepticus

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Review clinical trials related to Refractory Status Epilepticus. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Ketamine for the Treatment of Refractory Status Epilepticus

This pilot feasibility study aims to examine how the timing of ketamine introduction as a third-line anti-seizure medication infusion relates to seizure cessation in patients with refractory status epilepticus (RSE).

Participants needed: 50
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: Thomas Jefferson UniversityUpdated: Sep 16, 2025Locations: 1
Eligibility criteria

Adults 18 years of age or older [+4]

Exclusively psychogenic non epileptic seizures [+7]

Status: Recruiting

buRst-supprESsion TO Stop Refractory Status Epilepticus Post-cardiac Arrest

RESTORE is a randomized clinical trial investigating the safety and feasibility of using EEG treatment targets (burst suppression vs. seizure suppression) for post-cardiac arrest refractory status epilepticus treatment.

Participants needed: 30
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: University of California, San FranciscoUpdated: May 15, 2025Locations: 1
Eligibility criteria

Age ≥18 years old [+5]

Acute cerebral hemorrhage or infarction [+2]

Status: Recruiting

Application of tDCS Stimulation in Controlling Refractory Status Epilepticus

The purpose of the study is to assess the efficacy and safety of targeting tDCS stimulation for treatment of Refractory status epilepticus

Participants needed: 32
Trial details
Age: 14-80Biological sex: AllType: InterventionalSponsor: Xuanwu Hospital, BeijingUpdated: Jul 31, 2024Locations: 1
Eligibility criteria

Age between 14 and 80 year-old with Gender unlimited, [+3]

Unstable vital signs (systolic blood pressure<90mmHg, heart rate<60 beats/min, p... [+3]