Renal Oxygenation

1

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Condition / disease
Location
Status: Not yet recruiting

MR-Evaluation of Renal Function in Anesthetized Pediatric Patients

The goal of this study is to investigate the effect of the anesthetic agents sevoflurane or propofol on the blood flow and oxygen delivery to the kidneys. Pediatric patients who are planned to undergo an MRI scan with generalized anesthesia will be randomized to either IV anesthesia with propofol or inhalation anesthesia with sevoflurane. Both of these anesthetic methods are commonly used for anesthesia on an everyday basis. In addition to the clinically indicated MRI, Multiparametric MRI will be performed to visualize the effect of the anesthetic agent on renal blood flow, perfusion and oxygenation.

Participants needed: 50
Trial details
Phase: Phase 4Age: 1-14Biological sex: AllType: InterventionalSponsor: Uppsala UniversityUpdated: Mar 25, 2025
Eligibility criteria

Pediatric Patients (1 month -14 years of age) [+2]

Known renal impairment or chronic kidney disease [+6]