MR-Evaluation of Renal Function in Anesthetized Pediatric Patients
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age1-14
SponsorUppsala University
About this trial
The goal of this study is to investigate the effect of the anesthetic agents sevoflurane or propofol on the blood flow and oxygen delivery to the kidneys.
Pediatric patients who are planned to undergo an MRI scan with generalized anesthesia will be randomized to either IV anesthesia with propofol or inhalation anesthesia with sevoflurane. Both of these anesthetic methods are commonly used for anesthesia on an everyday basis.
In addition to the clinically indicated MRI, Multiparametric MRI will be performed to visualize the effect of the anesthetic agent on renal blood flow, perfusion and oxygenation.
Eligibility criteria
Qualifiers
Pediatric Patients (1 month -14 years of age)
Indicated for MRI with anesthesia
ASA (American Society of Anesthesiologists) physical status I-III
Disqualifiers
Known renal impairment or chronic kidney disease
Severe cardiac or pulmonary disease
Allergy to either Propofol or Sevoflurane
Contraindications to Magnetic Resonance Imaging
Trial design
Treatments tested in this trial
- Anesthesia Maintenance Agent
Treatment groups
50 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Uppsala University
Lead sponsor
Uppsala University Hospital
Collaborator
Source ClinicalTrials.gov