Reproductive Disorder

3

Review clinical trials related to Reproductive Disorder. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease

The objective of this protocol is to use a case-control paradigm to compare the response to an intravenous administration of kisspeptin in individuals with and without post-covid-19 syndrome. The study subjects will receive a single bolus of kisspeptin.

Participants needed: 40
Trial details
Phase: Phase 1Age: 18-60Biological sex: AllType: InterventionalSponsor: Stephanie B. Seminara, MDUpdated: Jul 13, 2026Locations: 1
Eligibility criteria

Female (ages 18-45 years) or Male (ages 18-60 years) [+4]

Any condition (medical, mental, or behavioral) that, in the opinion of a study i... [+6]

Status: Recruiting

Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease

The objective of this protocol is to use a case-control paradigm to compare the response to an intravenous administration of kisspeptin in individuals with and without post-covid-19 syndrome. The study subjects will receive a single bolus of kisspeptin. This study will utilize the technique of frequent blood sampling (q10 minutes) to provide detailed neuroendocrine characterization of endogenous LH secretion before and after kisspeptin administration. This frequency of blood sampling is required to define the features of LH pulses.

Participants needed: 40
Trial details
Phase: Phase 1Age: 18-60Biological sex: AllType: InterventionalSponsor: Stephanie B. Seminara, MDUpdated: May 19, 2026Locations: 1
Eligibility criteria

Female (ages 18-45 years) or Male (ages 18-60 years) [+6]

Any condition (medical, mental, or behavioral) that, in the opinion of a study i... [+7]

Status: Not yet recruiting

Autologous Decidual-like Natural Killer Cells Therapy for Reproductive Failure

The aim of this study is to verify the efficacy of in vitro induction of autologous decidual-like NK cells therapy for reproductive failure associated with uterine NK cells abnormalities.

Participants needed: 159
Trial details
Phase: Phase 2Age: 22-38Biological sex: FemaleType: InterventionalSponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolUpdated: Nov 17, 2025
Eligibility criteria

Reproductive failure with abnormal endometrial natural killer (NK) cells in mens... [+5]

Use of progesterone receptor modulators; [+7]