Rosacea

9

Review clinical trials related to Rosacea. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Transcutaneous Auricular Vagus Nerve Stimulation Treatment for Rosacea

A single arm, pilot study among individuals with rosacea and at least moderate flushing or rednesss will be enrolled in a 4-week trial of taVNS. The particicpants will be followed for an additional 4-weeks following the intervention period to evaluate the durability of the results

Participants needed: 10
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Brigham and Women's HospitalUpdated: May 22, 2026Locations: 1
Eligibility criteria

Adults aged 18 years of age and older [+3]

Changes to rosacea regimen (prescription topical or oral medications) within 4 w... [+14]

Status: Recruiting

Skin Inflammation in (Peri)Menopause: A Probiotic Intervention Proof of Concept Trial

This study will explore whether a daily probiotic drink containing Lactobacillus casei Shirota (LcS) can help improve immune function and reduce inflammation in women going through the menopausal transition. Hormonal changes during this stage of life can affect the immune system, gut health, and skin, sometimes leading to increased inflammation or conditions such as eczema, acne or rosacea. Participants will consume either a low-sugar LcS probiotic drink or a skimmed milk control drink every day for eight weeks. The study will assess markers of immune ageing, inflammation, skin health, wellbeing, and hormone levels. The results will help determine whether a safe, non-hormonal probiotic approach may support immune and skin health during the menopausal transition.

Participants needed: 30
Trial details
Age: 40-60Biological sex: FemaleType: InterventionalSponsor: King's College LondonUpdated: May 8, 2026Locations: 1
Eligibility criteria

Female, aged 40-60 years. [+8]

Inability or unwillingness to provide informed consent. [+26]

Status: Recruiting

Evaluating Use of Topical Imipramine and Amitriptyline in Reducing Ultraviolet B Light-Induced Redness in Patients With Rosacea

Rosacea is a common skin condition associated with easy blushing and red face; many patients with rosacea react to sunlight with increased redness. The purpose of this study is to determine if the use of a topical medication will help reduce sunlight induced redness and irritation in patients with rosacea.

Participants needed: 48
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Wright State UniversityUpdated: Feb 18, 2026Locations: 1
Eligibility criteria

Fitzpatrick Skin Type I - IIII [+2]

Using imipramine, amitriptyline or any other tricyclic antidepressant (oral or t... [+5]

Status: Recruiting

Acupuncture for Refractory Rosacea: A Study on Its Effectiveness and Safety

This study is a randomized, multicenter, sham-controlled clinical trial designed to evaluate the efficacy and safety of acupuncture for patients with refractory rosacea. A total of 104 participants will be enrolled and randomly assigned in a 1:1 ratio to the acupuncture group or the sham acupuncture group (52 participants in each group, regardless of sex). The primary aim is to determine whether acupuncture can effectively alleviate facial erythema and flushing episodes compared with sham stimulation.

Participants needed: 104
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Xiangya Hospital of Central South UniversityUpdated: Jan 30, 2026Locations: 1
Eligibility criteria

Patients diagnosed with refractory rosacea, defined as those who have received a... [+2]

Women who are pregnant, breastfeeding, or planning to become pregnant in the nea... [+9]

Status: Not yet recruiting

Vbeam Pro Pulse Dye Laser for the Treatment of Vascular Conditions

This is a clinical study to evaluate the safety and performance of the Vbeam Pro Laser System for the treatment of vascular indications, including rosacea and port wine stain birthmarks.

Participants needed: 40
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Candela CorporationUpdated: Dec 18, 2025
Eligibility criteria

Healthy subjects aged 18 years or older [+4]

Pregnant or planning to become pregnant, having given birth less than 3 months p... [+9]

Status: Recruiting

Determinants of Chronic Inflammatory Skin Disease Trajectories

Although it is well known that the clinical expression and course of chronic inflammatory skin diseases are highly variable, there are insufficient epidemiological data on this, and the factors that determine the manifestation, clinical features and course are also largely unknown. There are currently no reliable markers that could predict or delineate patient subgroups to support patient management. The aim of this project is to identify clinical and molecular factors that correlate with disease, disease subtypes and progression through in-depth long-term clinical characterization of patients with chronic inflammatory skin diseases and examination of individual biomaterials.

Participants needed: 1,000
Trial details
Age: 0-80Biological sex: AllType: ObservationalSponsor: University Hospital Schleswig-HolsteinUpdated: Jul 22, 2025Locations: 1
Eligibility criteria

dermatologist-diagnosed inflammatory skin disease [+1]

subject and/or the legal guardians are not able to give written informed consent [+4]

Status: Not yet recruiting

Clinical Evaluation and Study of the Efficacy of a Centella Asiatica-Infused Facial Mask on Discosmetic Dermatosis

The purpose of this study was to investigate the efficacy and safety of repairing facial mask containing Asiaticum asiatica in treating disjunctive skin diseases. A multi-center randomized double-blind self-half face control method was used. A computer-generated randomization method was used. Each cheek was randomly assigned to receive the snow glycoside mask and the control group.

Participants needed: 30
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: Nanjing First Hospital, Nanjing Medical UniversityUpdated: Jan 8, 2025Locations: 1
Eligibility criteria

Meet mild to moderate rosacea, acne diagnostic criteria; Meet the diagnostic cri... [+3]

Currently pregnant, planning to become pregnant or breastfeeding; [+6]

Status: Recruiting

Effects of Oral Supplement Containing L-Histidine and Antioxidants on the Skin Barrier Function and Systemic Inflammation in Rosacea

The purpose of this study is to evaluate how supplementation will alter the skin and the gut barrier and inflammation in those with rosacea.

Participants needed: 24
Trial details
Age: 30-70Biological sex: AllType: InterventionalSponsor: Integrative Skin Science and ResearchUpdated: Aug 27, 2024Locations: 1
Eligibility criteria

Males and females 30 to 70 years of age [+2]

The presence of severe rosacea as noted by the investigator global assessment. [+11]

Status: Recruiting

The Use of Image-Based Computer Gradings in the Analysis of Acne, Rosacea, Melasma, and Seborrheic Dermatitis

The study is conducted to determine if image-based computer grading can of acne, melasma, rosacea and seborrheic dermatitis correlate well to expert based clinical severity grading.

Participants needed: 150
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Integrative Skin Science and ResearchUpdated: Aug 27, 2024Locations: 1
Eligibility criteria

Adults with acne, rosacea, melasma or seborrheic dermatitis

Prisoners [+2]