Scoliosis Idiopathic Adolescent

11

Review clinical trials related to Scoliosis Idiopathic Adolescent. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

The Effect of Dexamethasone Administration Route and Local Anesthetic Concentration on Pain, Inflammatory Response, and Neuromonitoring in Children Undergoing Scoliosis Correction

Scoliosis correction surgery in children is a complex procedure with significant risks, including postoperative pain, inflammatory response, and potential neurological complications. Effective pain control and minimizing inflammation are critical for faster recovery and improved patient outcomes. Dexamethasone is commonly used as an adjuvant in regional anesthesia due to its anti-inflammatory effects and ability to prolong analgesia. However, limited research exists on the optimal route of dexamethasone administration (intravenous vs. perineural) and the best local anesthetic concentration for pain management, inflammatory response, and neuromonitoring during surgery. This study aims to compare the effects of different dexamethasone administration routes and local anesthetic concentrations on postoperative pain, inflammation (NLR, PLR), and neuromonitoring in pediatric scoliosis surgery. Results may improve regional anesthesia protocols, enhance patient safety, and offer valuable insights for clinical practice.

Participants needed: 60
Trial details
Phase: Phase 4Age: 10-18Biological sex: AllType: InterventionalSponsor: Poznan University of Medical SciencesUpdated: May 22, 2026Locations: 1
Eligibility criteria

>10 and <18 years old [+1]

included infection at the site of the regional block, [+4]

Status: Not yet recruiting

Deep Learning for Early Scoliosis Detection Using mmWave Radar Gait Data

Scoliosis is a sideways curvature of the spine that often develops during childhood and adolescence. When detected early, scoliosis can be managed effectively with non-invasive approaches such as bracing and physiotherapy, while late detection frequently leads to surgical intervention. Current screening methods rely on physical examination and X-ray imaging, which exposes children to ionizing radiation and may miss early-stage cases. This observational study investigates whether millimeter-wave (mmWave) radar, combined with deep learning (a type of artificial intelligence), can detect early signs of scoliosis by analyzing how a child walks. The radar sensor records subtle movement patterns during walking without using cameras and without producing any identifiable images, fully preserving the participant's privacy. No ionizing radiation is involved. Pediatric participants attending the orthopedic clinic for routine scoliosis evaluation are invited to walk a short distance in front of a mmWave radar sensor. The collected gait recordings are then analyzed using deep learning models, and the results are compared with the participant's standard clinical scoliosis assessment performed by a pediatric orthopedic specialist. The diagnostic performance of the deep learning model is evaluated using sensitivity, specificity, and overall accuracy. If the approach proves accurate, it could offer a radiation-free, privacy-preserving, and low-cost alternative for early scoliosis screening in schools, primary healthcare centers, and pediatric orthopedic clinics, ultimately supporting earlier diagnosis and reducing the long-term clinical burden of untreated scoliosis.

Participants needed: 200
Trial details
Age: 2-75Biological sex: AllType: ObservationalSponsor: Gebze Technical UniversityUpdated: May 18, 2026Locations: 1
Eligibility criteria

Being between 2 and 75 years of age at the time of registration [+4]

Severe scoliosis requiring urgent surgical intervention that prevents participat... [+1]

Status: Recruiting

Cyberchondria in Adolescents With Idiopathic Scoliosis

Scoliosis is a three-dimensional torsional deformity of the spine and trunk characterized by alignment abnormalities in the coronal plane, the presence of axial rotation in the horizontal plane, and abnormalities in the normal spinal curves (lordosis-kyphosis) in the sagittal plane. The most common type of scoliosis, adolescent idiopathic scoliosis (AIS), has a prevalence of approximately 3%. AIS accounts for 85% of all scoliosis types. AIS is the name given to scoliosis diagnosed between the ages of 10 and 18. Because they are actively engaged with the internet, young people have begun researching health-related topics online due to the ease of access to such information. The internet has overshadowed traditional sources of health information, such as social circles, mass media (television, radio, newspapers, magazines, etc.), and medical and non-medical health professionals; searching for medical information online has become a popular activity. Searching for medical information online appears to offer various advantages in terms of anonymity, cost-effectiveness, potential for interaction, opportunities for social support, and the amount of accessible information. However, it also carries significant drawbacks due to the risk of exposure to contradictory, confusing, unreliable, inaccurate, or outdated information. Cyberchondria is when a person's desire to research health-related symptoms online turns into excessive anxiety and repeated online searches. This can increase a person's health-related worries and fears and lead to mental health problems such as stress, anxiety, and depression. In today's information age, adolescents spend a large part of their day on the internet using smartphones and researching the symptoms of their current illnesses online before consulting a doctor or when they receive a diagnosis. This tendency can increase their anxiety levels due to misinformation. Cyberchondria is the reflection of anxiety in the digital age. Comorbidity in psychiatric disorders has generally been evaluated, but there are only a limited number of studies investigating the level of cyberchondria in a specific disease. There are no studies examining the relationship between cyberchondria and adolescent idiopathic scoliosis. This study aims to investigate the levels of cyberchondria and related factors in patients diagnosed with scoliosis and compare them with a control group.

Participants needed: 100
Trial details
Age: 12-20Biological sex: AllType: ObservationalSponsor: Izmir Democracy UniversityUpdated: May 7, 2026Locations: 1Duration: 1 Day
Eligibility criteria

Patients aged 12-20 years with a diagnosis of adolescent idiopathic scoliosis es... [+2]

Presence of a psychiatric disorder or use of psychotropic medications [+4]

Status: Not yet recruiting

Reliability of the Scoliosis Caregiver Response and Emotional Scale (SCaRES) Questionnaire

The aim of this study is to examine the psychometric properties of the Turkish version of the Scoliosis Caregiver Response and Emotional Scale (SCaRES) questionnaire; to evaluate the reliability of the Turkish form and to ensure its usability in clinical and research fields.

Participants needed: 23
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Hasan Kalyoncu UniversityUpdated: Dec 10, 2025Locations: 1
Eligibility criteria

Individuals who are an adult (parent or primary caregiver) responsible for the c... [+3]

Participants whose children have a history of other comorbidities (neurological,... [+4]

Status: Not yet recruiting

Reliability and Validity of the Adolescent Idiopathic Scoliosis - Truncal Anterior Asymmetry Scoliosis Questionnaire (TAASQ)

The survey examines how individuals with scoliosis define themselves and their physical appearance. Our aim in this study was to translate this survey into Turkish and demonstrate its reliability and validity.

Participants needed: 29
Trial details
Age: 10-18Biological sex: FemaleType: ObservationalSponsor: Hasan Kalyoncu UniversityUpdated: Dec 10, 2025Locations: 1
Eligibility criteria

Adolescent idiopathic diagnosis

Individuals who did not agree to participate in the study

Status: Recruiting

IntraVenous Iron in Kids With Iron Deficiency and Scoliosis Study

Adolescents and young adults undergoing spinal fusion surgery for the correction of scoliosis and other spinal deformity are at high risk of perioperative iron deficiency and anemia, yet the means and evidence for optimizing iron status have not been described in this setting. The proposed study is a randomized controlled trial of preoperative intravenous iron supplementation, to identify whether iron deficiency is a modifiable risk factor for adverse surgical outcomes such as red blood cell transfusion and diminished postoperative cognitive and physical capacity in this vulnerable population. Building evidence for patient blood management interventions such as iron supplementation is vital to ensuring high quality care of surgical patients and may reduce unnecessary transfusions amid recent blood shortages.

Participants needed: 120
Trial details
Phase: Phase 2, Phase 3Age: 10-19Biological sex: AllType: InterventionalSponsor: Columbia UniversityUpdated: Nov 26, 2025Locations: 1
Eligibility criteria

10 -19 years old [+3]

C-reactive protein > 10 mg/L [+8]

Status: Not yet recruiting

Investigating Proprioceptive Impairment in Adolescents With Idiopathic Scoliosis (AIS) (SCOLIO-PROPRIO)

The goal of this interventionnal study is to learn if teenagers who have severe scoliosis (a curvature of the spine) have trouble sensing their body's position in space (this sense is called proprioception), which are directly linked to abnormalities in the part of the brain that controls movement and/or caused by the muscles on each side of the spine not being the same size or not developing in the same way. The main question the investigators aim to answer are : * Do adolescents with severe scoliosis have problems with their sense of body position (proprioception)? * If so, are these proprioceptive issues linked to specific problems in the part of the brain that controls movement? * Are these proprioceptive issues also possibly linked to an uneven muscle structure on either side of the spinal curve? Researchers will compare the part of the brain that controls movement (ensorimotor brain network) of healthy subjects to that of the participants that will enroll in this study. Participants will only have to do one more MRI that is not included in the routine of clinical management of scoliosis before surgery. Data will also be retrieved from clinical practice Participants will answer questionnaires after the day of the surgery

Participants needed: 60
Trial details
Age: 10-18Biological sex: AllType: InterventionalSponsor: Assistance Publique Hopitaux De MarseilleUpdated: Oct 6, 2025Locations: 1
Eligibility criteria

Adolescents diagnosed with Adolescent Idiopathic Scoliosis (AIS) and followed in... [+4]

Presence of any other clinically significant condition that could be associated... [+7]

Status: Recruiting

Frontal/Axial and Self Body Image In Scoliosis

What is the relationship between frontal and axial back asymmetric parameters with self body image in adolescent idiopathic scoliosis Age This study will investigate the relationship between frontal and axial back asymmetry with self body image in adolescent idiopathic scoliosis Delimitations : patients will be diagnosed by orthopedic surgeon with adolescent idiopathic scoliosis Delimitations Age 11 to 18 years BMI fron 20 to 24.9kg/m2 Moderate cobbs angle 25-45 degrees Major thoacic curve Self body image will be ass by TAPS questionnaire which evaluate self image and satisfaction

Participants needed: 40
Trial details
Age: 11-18Biological sex: AllType: ObservationalSponsor: Al Hayah University In CairoUpdated: Sep 10, 2025Locations: 1
Eligibility criteria

Both gender's adolescent idiopathic scoliosis Age from 11 to 18 years Body mass...

leg length discrepancy Any mental condition Defects of spinal vertebrae Previous...

Status: Recruiting

Augmented Reality-Assisted Physiotherapy for Adolescents With Idiopathic Scoliosis: A Qualitative Study

This study aims to explore the effects of augmented reality (AR)-supported physiotherapy on body awareness, motivation, and exercise adherence in adolescents diagnosed with Adolescent Idiopathic Scoliosis (AIS). Using a qualitative phenomenological approach, the study will involve semi-structured interviews with adolescents who have completed at least four weeks of AR-based physiotherapeutic scoliosis-specific exercises. The goal is to understand participants' lived experiences with AR-enhanced rehabilitation and to inform the development of adolescent-centered, technology-integrated physiotherapy strategies in conservative scoliosis care.

Participants needed: 15
Trial details
Age: 10-18Biological sex: AllType: InterventionalSponsor: Hasan Kalyoncu UniversityUpdated: Jul 16, 2025Locations: 1
Eligibility criteria

Aged between 10 and 18 years [+4]

Presence of neurological or cognitive conditions interfering with communication [+2]

Status: Not yet recruiting

Investigation on the Prevalence and Etiology of Adolescent Idiopathic Scoliosis in Nanchang Region

The purpose of this study is to investigate the prevalence and etiology of adolescent idiopathic scoliosis in the Nanchang region. Elementary and middle school students who met the inclusion criteria were included in the study and school-based scoliosis screening was conducted. Diagnosis of suspected scoliosis was determined by physical examination, Adams forward bend test, measurement of trunk rotation angle, and Standing Anteroposterior X-ray of the Spine. The prevalence of suspected scoliosis among elementary and middle school students was calculated. At the same time, the researchers kept detailed records of all costs incurred in the school screening.

Participants needed: 400
Trial details
Age: 9-14Biological sex: AllType: ObservationalSponsor: Nanchang University Affiliated Rehabilitation HospitalUpdated: May 30, 2025Locations: 1Duration: 1 Day
Eligibility criteria

Age 9-14 years old, enrolled in elementary or middle school. [+3]

Severe Medical Conditions: Individuals with severe diseases of the heart, liver,... [+3]

Status: Not yet recruiting

Effectiveness of Kinesiotaping in Adolescent Idiopathic Scoliosis

The effectiveness of kinesiotaping application in addition to exercise in Adolescent Idiopathic Scoliosis will be compared on the pain level with the numerical rating scale, the Cobb angle and scoliometer measurements, the quality of life with the Scoliosis Research Association-22 quality of life scale, and the patient's visual perception level with the Walter Reed visual assessment scale. Research Group: In addition to the regular exercise program, kinesio taping will be applied to patients diagnosed with Adolescent Idiopathic Scoliosis. Kinesio taping will be applied for 5 days on and 2 days off for 4 weeks. Control Group: Patients diagnosed with Adolescent Idiopathic Scoliosis will continue their regular exercise program. No intervention will be applied. Patients will be evaluated before and 3 months after treatment in terms of pain level with numerical rating scale, Cobb angle measurement and Scoliometer measurement, quality of life with Scoliosis Research Association-22 quality of life scale and Walter Reed visual assessment scale.

Participants needed: 54
Trial details
Age: 10-18Biological sex: AllType: InterventionalSponsor: Sisli Hamidiye Etfal Training and Research HospitalUpdated: Mar 30, 2025
Eligibility criteria

Being under follow-up with the diagnosis of Adolescent Idiopathic Scoliosis [+3]

Having a spinal curvature of more than 25 degrees [+3]