Toothbrushing

3

Review clinical trials related to Toothbrushing. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Clinical ,Microbiological and Compliance Outcomes of AI-based Toothbrushes in Plaque Induced Gingivitis

Severe periodontitis is widespread and begins with reversible gingivitis, driven by poor oral hygiene and a dysbiotic microbiome. Daily toothbrushing is the simplest prevention, but patients still leave plaque. Electric brushes remove more plaque and reduce gingivitis better than manual ones, and users show better periodontal status. App-connected smart brushes and apps aim to improve adherence. Trials increased plaque reduction and brushing time versus manual brushing, but app layers have not clearly beaten standard power brushes, and microbiological outcomes are rarely reported. Xiaomi's AI-based sonic T501 adds pressure sensing, personalised coaching and coverage tracking, whereas the T302 is a simpler non-connected sonic brush. Streptococcus sanguinis is a health-associated early coloniser; its qPCR-measured relative abundance marks a healthy supragingival profile. It is still unclear whether AI guidance adds extra benefit beyond a standard electric brush in adult gingivitis.

Participants needed: 33
Trial details
Age: 18-35Biological sex: AllType: InterventionalSponsor: University of BaghdadUpdated: Dec 29, 2025Locations: 1
Eligibility criteria

Participants should be systemically healthy [+3]

Participants who using antibiotics or anti-inflammatory medication throughout th... [+8]

Status: Recruiting

Evaluation of a Novel Dual-Headed Toothbrush Design for Periodontal Health: Split-Mouth Randomized Blind Clinical Trial

The goal of this clinical trial is to evaluate the effectiveness and patient satisfaction of a novel dual-headed toothbrush design compared to a conventional single-headed toothbrush in adult dental professionals aged 22-45 years with healthy gingival conditions. The main questions it aims to answer are: Does the dual-headed toothbrush improve plaque removal efficiency compared to a single-headed toothbrush? Does the dual-headed toothbrush enhance brushing comfort, reduce brushing time, and improve user satisfaction? Researchers will compare the side of the mouth (cleaned with a dual-headed toothbrush) with the other side (cleaned with a single-headed toothbrush) in a randomized split-mouth design to see if the novel design leads to superior plaque control and better user experience. Participants will: Receive both toothbrush types (medium bristle) and identical toothpaste Be trained in the Bass brushing technique Use each toothbrush, twice daily, with the assigned toothbrush applied to its designated side of the mouth Complete post-trial questionnaires on comfort, ease of use, and brushing time

Participants needed: 40
Trial details
Age: 25-40Biological sex: AllType: InterventionalSponsor: Dar Al Uloom UniversityUpdated: Sep 11, 2025Locations: 1
Eligibility criteria

• Dentists with a minimum of 26 natural teeth, good general health, and the abil... [+3]

• Participants with active periodontal disease, orthodontic appliances, or havin... [+2]

Status: Recruiting

Effectiveness of Dual Light Electric Toothbrush vs. Manual Toothbrush in Orthodontic Patients Undergoing Oral Surgery

The study is a randomized clinical trial to compare the effectiveness of a dual light ultrasonic toothbrush on periodontal health in orthodontic patients undergoing surgery. Patients with cleft lip and palate undergo bone graft and orthognathic surgery. The study will compare the periodontal outcomes in patients who use these toothbrushes during the post-surgical period.

Participants needed: 198
Trial details
Age: 6-20Biological sex: AllType: InterventionalSponsor: Children's Hospital Los AngelesUpdated: May 13, 2024Locations: 1
Eligibility criteria

Patient of record of the Craniofacial and Special Care Orthodontic Clinic at Chi... [+3]

physical inability to brush teeth [+1]