Clinical ,Microbiological and Compliance Outcomes of AI-based Toothbrushes in Plaque Induced Gingivitis

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-35
SponsorUniversity of Baghdad

About this trial

Severe periodontitis is widespread and begins with reversible gingivitis, driven by poor oral hygiene and a dysbiotic microbiome. Daily toothbrushing is the simplest prevention, but patients still leave plaque. Electric brushes remove more plaque and reduce gingivitis better than manual ones, and users show better periodontal status. App-connected smart brushes and apps aim to improve adherence. Trials increased plaque reduction and brushing time versus manual brushing, but app layers have not clearly beaten standard power brushes, and microbiological outcomes are rarely reported. Xiaomi's AI-based sonic T501 adds pressure sensing, personalised coaching and coverage tracking, whereas the T302 is a simpler non-connected sonic brush. Streptococcus sanguinis is a health-associated early coloniser; its qPCR-measured relative abundance marks a healthy supragingival profile. It is still unclear whether AI guidance adds extra benefit beyond a standard electric brush in adult gingivitis.

Eligibility criteria

Qualifiers

Participants should be systemically healthy

18 years old, with the presence of ≥ 20 teeth

Diagnosed with generalized plaque-induced gingivitis having >30% bleeding sites, with probing depths ≤3 mm and intact periodontium

Participants with at least secondary school education, who are able to read and understand basic English to follow the app-based toothbrush instructions

Disqualifiers

Participants who using antibiotics or anti-inflammatory medication throughout the investigation or during the previous 3 months prior to the study.

Drug-induced gingival enlargement (phenytoin, cyclosporine, calciumchannel blockers).

Individuals with periodontitis and healthy periodontium.

Mouth breathers .

Trial design

Treatments tested in this trial

  • AI toothbrush
  • Manual toothbrush
  • Electric toothbrush

Treatment groups

33 Participants
are divided into 3 treatment groups

Sponsors and collaborators