Total Knee Arthroplasty Recovery

6

Review clinical trials related to Total Knee Arthroplasty Recovery. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Effects of Progressive Restricted Blood Flow Exercises in Post Total Knee Arthroplasty

Total knee arthroplasty (TKA) is a commonly performed procedure for advanced knee osteoarthritis. Despite successful surgery, many patients experience postoperative impairments including pain, reduced range of motion (ROM), swelling, impaired proprioception, and kinesiophobia, which may delay functional recovery. Conventional physiotherapy is the standard rehabilitation approach following TKA; however, high-load strengthening exercises are often limited in the early postoperative phase due to pain and reduced tolerance. Blood flow restriction (BFR) exercise is an emerging rehabilitation technique that enables low-load exercise to produce strength adaptations similar to high-intensity training. While evidence supports its effectiveness for improving muscle strength, its effects on other outcomes such as pain, swelling, proprioception, and kinesiophobia are not well established. This randomized controlled trial will compare progressive BFR exercise combined with conventional physiotherapy versus conventional physiotherapy alone in patients following unilateral TKA. A total of 48 participants will be randomly allocated to two groups. The intervention will be delivered over 6 weeks with supervised sessions conducted three times per week. Outcomes will include pain, knee ROM, swelling, proprioception, kinesiophobia, and functional performance. This study aims to determine whether BFR exercise provides additional benefits in postoperative rehabilitation following TKA.

Participants needed: 48
Trial details
Age: 50-65Biological sex: AllType: InterventionalSponsor: Lahore University of Biological and Applied SciencesUpdated: Jun 9, 2026Locations: 1
Eligibility criteria

Patients of age 50-65 years. [+4]

History of deep vein thrombosis within the last six months. [+3]

Status: Recruiting

The Effects of Mir Shakeel Teleintegrated Therapy Plan in Patients Undergoing Total Knee Arthroplasty

This randomized controlled trial aims to evaluate the effectiveness of a newly developed Modified Structured Telerehabilitation Intervention Protocol (MSTITP) compared with conventional in-person physical therapy in patients recovering from Total Knee Arthroplasty (TKA). The study also explores whether a hybrid rehabilitation approach may further optimize patient outcomes. A total of eligible participants aged 50-65 years who have undergone primary TKA will be randomly assigned to one of two groups: Group A (Intervention): Telerehabilitation-based structured exercise program (MSTITP) delivered through digital platforms with remote supervision. Group B (Control): Standard conventional face-to-face physiotherapy in a clinical setting. Both groups will receive rehabilitation programs of equal duration focusing on pain management, range of motion (ROM), muscle strengthening, gait training, and functional mobility. The primary objective is to compare the effectiveness of telerehabilitation and conventional therapy in improving pain, ROM, and gait performance. Secondary objectives include evaluation of exercise adherence, kinesiophobia, functional outcomes, quality of life, and patient satisfaction. Additionally, the study will explore whether integrating telerehabilitation with conventional rehabilitation could provide superior outcomes. Outcome assessments will be conducted using validated tools including pain scales (VAS), goniometric ROM measurements, gait analysis, functional performance tests, and standardized questionnaires for quality of life, exercise adherence, and fear of movement. This study addresses the increasing burden of osteoarthritis and the growing number of TKA procedures in Pakistan. Telerehabilitation may offer a cost-effective, accessible, and scalable rehabilitation model that ensures continuity of care and improved access to physiotherapy services, particularly in resource-limited settings. The findings of this trial are expected to provide evidence for developing standardized, technology-assisted rehabilitation protocols to improve post-TKA recovery outcomes and reduce healthcare burden.

Participants needed: 120
Trial details
Age: 50-65Biological sex: AllType: InterventionalSponsor: Lincoln University CollegeUpdated: May 13, 2026Locations: 1
Eligibility criteria

Patients who have underwent a primary unilateral total knee arthroplasty due to... [+3]

Presence of significant comorbidities or complications that could interfere with... [+4]

Status: Not yet recruiting

Effects of Stress Ball Use and Breathing Exercises on Pain and Vital Signs During Drain Removal After Total Knee Arthroplasty

This randomized controlled trial aims to evaluate the effects of stress ball use and breathing exercises on procedural pain and vital signs during drain removal in patients undergoing total knee arthroplasty. Although drain removal is a short procedure, it is often associated with sudden and intense pain and may trigger physiological stress responses such as increased heart rate, blood pressure, and respiratory rate. A total of 105 patients will be randomly assigned to three groups: stress ball group, breathing exercise group, and standard care group. The interventions will be applied starting one minute before drain removal, continuing throughout the procedure, and for two minutes afterward. Pain levels will be assessed using the Numeric Rating Scale (NRS), and vital signs (heart rate, blood pressure, respiratory rate, and oxygen saturation) will be measured at predefined time points before, during, and after the procedure. The findings of this study are expected to provide evidence on the effectiveness of simple, non-pharmacological interventions in reducing procedural pain and improving physiological stability during drain removal

Participants needed: 105
Trial details
Biological sex: AllType: InterventionalSponsor: TC Erciyes UniversityUpdated: May 14, 2026
Eligibility criteria

Adults aged 18 years and older undergoing primary total knee arthroplasty [+3]

Patients with chronic pain syndromes or regular opioid use [+3]

Status: Recruiting

Femoral Triangle Block vs Adductor Canal Block on Early Quadriceps Function After Total Knee Arthroplasty

The goal of this clinical trial is to compare the effects of femoral triangle block (FTB) and adductor canal block (ACB) on early quadriceps function after total knee arthroplasty (TKA). The main question it aims to answer is whether FTB causes more early quadriceps functional impairment than ACB under a standardized multimodal analgesia protocol. Researchers will compare FTB and ACB using a composite binary functional outcome measured 6 hours after block completion. Quadriceps functional impairment is defined as the inability to perform a structured straight leg raise or quadriceps muscle strength \<50% of the preoperative baseline. Participants will be randomly assigned to receive ultrasound-guided FTB or ACB. All participants will also receive a popliteal plexus block and standardized multimodal analgesia.

Participants needed: 136
Trial details
Age: 20+Biological sex: AllType: InterventionalSponsor: Social Medical Corporation DaiyukaiUpdated: Apr 16, 2026Locations: 1
Eligibility criteria

Adult patients (≥ 20 years of age) are scheduled to undergo primary unilateral T... [+5]

Known allergy or contraindication to local anesthetic agents used in this study. [+5]

Status: Not yet recruiting

Mirror Therapy as an Adjunct to Rehabilitation Following Total Knee Arthroplasty

The investigators are looking to see if using a mirror during knee exercises after a knee replacement helps participants with less pain and/or better knee range of motion.

Participants needed: 30
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: State University of New York - Upstate Medical UniversityUpdated: Feb 2, 2026
Eligibility criteria

Candidates that have been screened and deemed eligible for a TKA and received a... [+5]

Post-surgical complications (DVT, infection, nerve injury, vascular injury) [+3]

Status: Recruiting

The Effect of Balance Training Using a Dynamometric Platform in Patients Undergoing Total Knee Arthroplasty

Total knee arthroplasty (TKA) is a common surgery used to treat advanced knee osteoarthritis, especially when other treatments no longer help. While the surgery often reduces pain and improves joint alignment, many patients still have problems with balance and movement afterward. This study will explore whether adding balance training using the Tecnobody ProKin system to standard physical therapy helps patients recover better after TKA. The researchers will measure balance, walking ability, leg strength, and body awareness (also called proprioception) using special equipment. The main goal is to test the hypothesis that technology-supported balance training improves recovery outcomes more effectively than standard rehabilitation alone.

Participants needed: 46
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Ankara Etlik City HospitalUpdated: Jul 23, 2025Locations: 1
Eligibility criteria

Patients who have undergone total knee arthroplasty within the past 2 years and... [+2]

Bilateral knee arthroplasty [+11]