Vaginal Delivery

9

Review clinical trials related to Vaginal Delivery. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

USE OF PERINEAL MIRROR DURING THE SECOND STAGE OF LABOR

Objective: This study was designed to evaluate the effect of perineal mirror use during the second stage of labor on the duration of the second stage, postpartum recovery, and perceived pain, support, and control levels during delivery. Method: The study was designed as a randomized controlled experimental study to examine the effect of perineal mirror use on delivery outcomes in primiparous women. The study population consisted of primiparous pregnant women admitted to the maternity clinic between June 29, 2026, and October 30, 2026. The sample size was calculated using the G\*Power 3.1.9.2 program with an effect size of 0.50, 5% Type I error, and 95% power level; a total of 72 participants were selected, 36 in the intervention group and 36 in the control group. Considering potential losses, the sample size was increased by 10%, and a total of 80 pregnant women were planned to be included in the study. Participants were randomly assigned to the intervention group using a perineal mirror and the control group receiving routine care. The following instruments will be used as data collection tools: Pregnancy Demographic Information Form, REEDA Scale, Visual Analog Scale (VAS), and Perceived Support and Control in Childbirth Scale. Expected Outcome: It is predicted that the perineal mirror may increase the woman's active participation, motivation, and perceived control by allowing her to see the fetal descent and the progress of labor; consequently, it may reduce the duration of active pushing and the duration of the second stage. It is also thought that it may have positive effects on the birth experience, postpartum recovery, and perceived level of support and control. The research results are expected to provide evidence for non-invasive and low-cost applications that can be used in childbirth care.

Participants needed: 80
Trial details
Age: 19-49Biological sex: FemaleType: InterventionalSponsor: Sakarya UniversityUpdated: Jun 22, 2026Locations: 1
Eligibility criteria

Women aged 19 and over [+5]

Women with high-risk pregnancies [+1]

Status: Recruiting

Practice of Assisted Vaginal Birth in Egypt

In Egypt, the proportion of CSs has been steadily increasing in recent years and has reached an alarming level. According to data from the Royal College of Obstetricians and Gynaecologists (RCOG), approximately 6% of caesarean sections (CS) are performed on average because of inadequate supervision from junior staff members or a lack of training, particularly during the critical decision-making phase of this second stage. The unfamiliarity and lack of experience with operative vaginal delivery is a major cause for the rise in the rate of second stage caesarean section. This survey targets obstetricians with different levels of experience to find practical solutions to increase the rate of assisted vaginal delivery which subsequently will decrease the rate of second stage CS.

Participants needed: 150
Trial details
Age: 28-60Biological sex: AllType: ObservationalSponsor: Ain Shams Maternity HospitalUpdated: May 12, 2026Locations: 1
Eligibility criteria

Obstetricians with at least 3 years of experience in practicing obstetrics [+1]

Status: Recruiting

Infant Microbiota Restoration With Maternal Microbes

The goal of this clinical trial is to test the ability of different bacterial products in restoring natural gut microbiota in C-section born infants. The main question it aims to answer is: Do maternally derived strains of bacteria perform better than commercially available probiotic strains in restoring the gut microbiota of C-section born infants? Researchers will compare the gut microbiota of treated infants to that of untreated C-section born infants and untreated vaginally born infants to see if the bacterial treatments cause the microbiota to resemble that of vaginally born infants. Participants will be given a bacterial product orally once daily for either one or four weeks and be asked to collect faecal, urine and saliva samples.

Participants needed: 100
Trial details
Age: Up to 50Biological sex: AllType: InterventionalSponsor: University of HelsinkiUpdated: Oct 8, 2025Locations: 2
Eligibility criteria

Healthy mother and healthy pregnancy [+4]

Participants who lives further than a 2-hour drive from Meilahti, Helsinki, Finl... [+7]

Status: Recruiting

Comparative Analysis of Analgesic Efficacy: by Single Shot Intrathecal Analgesia (SSSA) in Normal Labor

the goal of this randomized control trial is to compare the effect of adding fentanyl v.s dexmedetomidine to bupivacaine in single shot spinal analgesia in achievement of analgesia by decreasing visual analogue scale, onset and increasing duration of analgesia in normal labor.

Participants needed: 90
Trial details
Phase: Phase 4Biological sex: FemaleType: InterventionalSponsor: Jehan George SadekUpdated: Jul 31, 2025Locations: 1
Eligibility criteria

ASA I-II. [+4]

Patient refusal. [+4]

Status: Not yet recruiting

Outcomes of Delivery in Primigravida

Primigravida women are a high-priority population due to their increased risk of obstetric interventions and adverse outcomes compared to multiparous women. Research indicates that first-time mothers account for a disproportionate number of emergency cesarean sections and instrumental deliveries, often due to factors such as inadequate labor support or failure to progress

Participants needed: 200
Trial details
Biological sex: FemaleType: ObservationalSponsor: Assiut UniversityUpdated: Jul 24, 2025
Eligibility criteria

Primigravida women admitted for delivery at the hospital [+3]

• Multiparous women. [+3]

Status: Not yet recruiting

Factors Affecting Success of Vaginal Birth After Cesarean Section

Factors affecting Success of Vaginal Birth After Cesarean Section in Sohag University Hospitals

Participants needed: 1
Trial details
Age: 20-40Biological sex: FemaleType: ObservationalSponsor: Sohag UniversityUpdated: Nov 8, 2024
Eligibility criteria

• Age from 20 to 40 years. [+7]

• Women with previous upper segment cesarean section or hysterotomy scar. [+5]

Status: Not yet recruiting

Ultrasound Parameters for the Outcome Prediction of External Cephalic Version for Fetuses with Breech Presentation

This study aims to evaluate possible predictors for the successful od external cephalic version (ECV), a procedure that is indicated in your case due to breech presentation of your baby and your desire to avoid cesarean section. Before the procedure, a detailed ultrasound scan will be performed to measure several parameters. After the procedure we will collect data about the duration, outcome and eventual complications of ECV.

Participants needed: 120
Trial details
Age: 18+Biological sex: FemaleType: ObservationalSponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCSUpdated: Sep 19, 2024
Eligibility criteria

Age ≥18 y.o.; [+6]

Age <18 y.o.; [+12]

Status: Recruiting

Lignocaine vs Bupivacaine Infiltration for Postpartum Perineal Pain After Vaginal Delivery With Episiotomy in Primigravidae

In this study, we will compare the effect and safety of lignocaine versus bupivacaine infiltration for postpartum perineal pain after vaginal delivery with episiotomy in primigravidae.

Participants needed: 60
Trial details
Age: 18-40Biological sex: FemaleType: InterventionalSponsor: Ain Shams UniversityUpdated: Aug 23, 2024Locations: 1
Eligibility criteria

Primigravidae with the full term undergoing vaginal delivery with episiotomy. [+2]

Patients with history of drug allergies to study drugs as this will increase the... [+7]

Status: Not yet recruiting

A Novel Approach Integrating Magnetic Resonance Imaging (MRI) Data and Artificial Intelligence for Predicting the Success Rate of Vaginal Delivery in Pregnant Women

The aim of this study was to use MRI imaging to accurately scan the pregnant woman's pelvis and fetal skull, build a 3D model of them, and combine with artificial intelligence to develop an accurate tool to predict the success rate of vaginal delivery.

Participants needed: 200
Trial details
Age: 18-35Biological sex: FemaleType: ObservationalSponsor: Second Affiliated Hospital of Wenzhou Medical UniversityUpdated: Sep 21, 2023Locations: 1
Eligibility criteria

Full-term. [+3]

Pregnancy with serious medical and surgical diseases. [+3]