Clinical trials

4

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

Finerenone will be compared to placebo to determine efficacy and safety of treatment in patients hospitalized with acute decompensated heart failure (HF) and mildly reduced or preserved left ventricular ejection fraction.

Participants needed: 5,200
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Colorado Prevention CenterUpdated: May 6, 2026Locations: 299
Eligibility criteria

Provide written informed consent [+5]

Current or planned long-term treatment with a mineralocorticoid receptor antagon... [+8]

Status: Recruiting

Implementation of an Algorithm- and Multi-professional Team-supported Strategy to Improve Lipid Management of Patients With Atherosclerotic Cardiovascular Disease

This is a randomized, controlled, collaborative, multicenter, pilot implementation science study evaluating the hypothesis that algorithm- and multi-professional team-supported lipid management reduces low density lipoprotein-cholesterol (LDL-C) compared with usual care in patients with atherosclerotic cardiovascular disease (ASCVD).

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Colorado Prevention CenterUpdated: Jan 23, 2026Locations: 1
Eligibility criteria

Provided informed consent [+6]

Any reason that, in the opinion of the investigator, the patient would be unable... [+2]

Status: Recruiting

A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients with Heart Failure Who Are Intolerant or Not Eligible for Treatment with Steroidal Mineralocorticoid Receptor Antagonists

Finerenone will be compared to placebo to determine efficacy and safety of treatment in patients with heart failure and reduced ejection fraction (HFrEF) who are intolerant or ineligible to receive treatment with steroidal mineralocorticoid receptor antagonists (sMRA).

Participants needed: 2,600
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Colorado Prevention CenterUpdated: Mar 11, 2025Locations: 8
Eligibility criteria

Provide electronic or written informed consent, either personally or through a l... [+4]

Treatment with non-steroidal MRA (nsMRA) [+12]

Status: Recruiting

A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients with Heart Failure (CONFIRMATION-HF)

Combination therapy of finerenone plus empagliflozin will be compared to usual care to determine the efficacy and safety of treatment in patients hospitalized with heart failure.

Participants needed: 1,500
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Colorado Prevention CenterUpdated: Mar 11, 2025Locations: 15
Eligibility criteria

Provide electronic or written informed consent, either personally or through a l... [+7]

Diagnosis of type 1 diabetes or prior history of diabetic ketoacidosis [+11]