About this trial
This is a randomized, controlled, collaborative, multicenter, pilot implementation science study evaluating the hypothesis that algorithm- and multi-professional team-supported lipid management reduces low density lipoprotein-cholesterol (LDL-C) compared with usual care in patients with atherosclerotic cardiovascular disease (ASCVD).
Eligibility criteria
Qualifiers
Provided informed consent
Age >18 years inclusive at screening
Coronary artery disease (prior revascularization, myocardial infarction, imaging evidence of coronary atherosclerosis)
Peripheral artery disease (prior revascularization, amputation, ankle: brachial index (ABI) ≤ 0.90, imaging evidence of extra-coronary atherosclerosis)
Disqualifiers
Any reason that, in the opinion of the investigator, the patient would be unable to adhere to the protocol for the duration of the study (e.g. terminal diagnosis, metastatic cancer) or in whom participation might result in harm.
Planned active titration of current lipid-lowering therapy
Myocardial infarction or arterial revascularization within prior 30 days
Trial design
Treatments tested in this trial
- Algorithm- and multi-professional team-supported lipid management
- Guideline-directed lipid management by usual care provider