Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Theta Burst Stimulation With an 8-Coil Versus H1-Coil for Resistant Depression

The goal of this clinical trial is to compare response rates after treatment with Figure Eight-Coil TMS versus H-Coil TMS on the prefrontal cortex left dorsolateral, in patients suffering from depression resistant. The main question it aims to answer is: rTBS (accelerated neuronavigated intermittent Theta Burst Stimulation) is more effective than hTBS (accelerated deep intermittent Theta Burst Stimulation) in the treatment of resistant depression in terms of response rate.? Researchers will compare Figure Eight-Coil TMS (rTBS) versus H-Coil TMS (hTBS) to see if rTBS is more effective than hTBS. Participants will: * Receive, for each stimulation method, 8 sessions per day spaced 50 minutes apart, over 5 days. * Have visit all day of stimulation for checkups and tests. * Have a a research MRI before and after treatment. * Have follow-up visits at 1 month, 2 months, 3 months, 6 months, and 12 months post-treatment, via teleconsultation.

Participants needed: 108
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Dominique JANUELUpdated: Feb 6, 2025
Eligibility criteria

Patients over 18 years of age [+5]

Presence of a contraindication to TMS: epilepsy, intracranial foreign body, coch... [+11]

Status: Recruiting

Evaluation of the Efficacy of Transcranial Magnetic Stimulation on Resistant Auditory Hallucinations in Schizophrenia

This open naturalistic study aims to evaluate the efficacy of rTMS in routine practice on auditory resistant hallucinations (AHR) of patients with schizophrenia. To this end, two stimulation methods will be offered to patients: the rTMS stimulation method and the cTBS stimulation method.We principally use the AHRS scale to evaluate the effectiveness of rTMS on RAH in patients with schizophrenia. Our main hypothesis is that rTMS used under naturalistic conditions, in addition to antipsychotics, would allow a relative improvement of resistant auditory hallucinations assessed by the AHRS scale between baseline and end of treatment in patients with schizophrenia.

Participants needed: 30
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Dominique JANUELUpdated: Sep 19, 2024Locations: 1
Eligibility criteria

Patient over 18 years of age [+6]

Have a contraindication to MST: intracranial foreign body, unstabilized epilepsy... [+9]

Status: Recruiting

EMDR Pre-treatment Yoga for Complex Trauma

yoga is a technique of hope. Indeed, it is a practice that specifically combines postures, breathing technique and a state meditative. The combination of these elements produces multiple effects that are exposed to detailed in the publications of Bessel Van der Kolk (Price et al., 2017; Rhodes, Spinazzola, \& van der Kolk, 2016; Van der Kolk, 2014; Van Der Kolk et al., 2014) and whose four main effects are summarized here: * A regulation of the level of vigilance * An improvement in self-awareness * An increased sense of self-efficacy * Improved metacognition, awareness and regulation emotional

Participants needed: 66
Trial details
Age: 18-70Biological sex: FemaleType: InterventionalSponsor: Dominique JANUELUpdated: Mar 6, 2024Locations: 2
Eligibility criteria

Meets diagnostic criteria for Complex Post-traumatic Stress Disorder according t... [+3]

Pregnant women [+8]