Status: Recruiting
Single and Twice-daily Dosing of Ramipril on Renal Function in Chronic Kidney Disease Patients With Reduced Ejection Fraction Heart Failure
This study compares the effects of once-daily versus twice-daily ramipril dosing on renal function in chronic kidney disease (CKD) patients with heart failure with reduced ejection fraction (HFrEF). Outcomes include changes in plasma renin activity, malondialdehyde, interleukin-6, albuminuria, and cystatin C after 30 days of therapy.
Participants needed: 80
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: Evi Liliek WulandariUpdated: Dec 10, 2025Locations: 1
Eligibility criteria
Female or Male with age >18 years old [+1]
Receiving hemodialysis therapy [+7]