Clinical trials

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Status: Not yet recruiting

Based on the Spatio-temporal Coding Characteristics of Frontotemporal Network, This Paper Explores the Mechanism of Five-tone Speech Training in Reshaping Language Fluency Function.

To explore the mechanism of five-tone speech training in reshaping language fluency function and the clinical efficacy of aphasia language function, daily communication ability and communication efficiency based on the temporal and spatial coding characteristics of frontotemporal network. Combined with EEG ( rsEEG, ERP ), nuclear magnetic resonance examination and near-infrared imaging system examination to explore its effect on brain electrophysiological activity. So as to promote the modernization of traditional Chinese medicine rehabilitation treatment technology and the popularization and application of speech rehabilitation treatment technology.

Participants needed: 120
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Fujian University of Traditional Chinese MedicineUpdated: Jan 21, 2026
Eligibility criteria

Not listed

Status: Not yet recruiting

To Explore the Functional Connectivity Pattern of Cortical Swallowing Network in the Oral Phase of Post-stroke Dysphagia Based on Dynamic Causal Modelling

Swallowing activity in the oral phase is regulated by the cortical swallowing network, and the functional connectivity pattern of the cortical swallowing network is related to swallowing activity. The structural damage of the cortical swallowing network and abnormal activation of brain areas related to swallowing in post-stroke dysphagia affect swallowing activity. The recovery of dysphagia after stroke is related to the compensation of swallowing network in the contralateral hemisphere and different connectivity patterns of diseased brain areas, and the integrity of cortical swallowing network connectivity affects the sequence of oral swallowing activities. However, it is not clear how the functional connectivity patterns and interactions of brain regions of the cortical swallowing network related to oral swallowing activity change in patients with oral dysphagia after stroke.

Participants needed: 72
Trial details
Age: 18-80Biological sex: AllType: ObservationalSponsor: Fujian University of Traditional Chinese MedicineUpdated: Aug 21, 2024
Eligibility criteria

Patients with dysphagia after first stroke, meeting the diagnostic criteria of s... [+18]

Dysphagia not caused by stroke or non-oral dysphagia; [+6]