Clinical trials

6

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Mass Balance Study Of 14C-RAY1225 Injection In Healthy Chinese Participants

This is an open-label, single-center, single-dose study.

Participants needed: 8
Trial details
Phase: Phase 1Age: 18-55Biological sex: AllType: InterventionalSponsor: Guangdong Raynovent Biotech Co., LtdUpdated: Mar 10, 2026Locations: 1
Eligibility criteria

Participants who sign the informed consent form, fully understand the content, p... [+3]

Subjects with trauma, surgical scar, or skin lesions at the proposed administrat... [+5]

Status: Not yet recruiting

A Study of RAY1225 Versus Semaglutide as Add-on Therapy to Oral Antidiabetic Drugs in Participants With Type 2 Diabetes

The reason for this study is to compare the effect of the study drug RAY1225 to semaglutide on blood sugar levels in participants with type 2 diabetes.

Participants needed: 600
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Guangdong Raynovent Biotech Co., LtdUpdated: Aug 24, 2025Locations: 1
Eligibility criteria

Have been diagnosed with type 2 diabetes mellitus (T2DM) [+3]

Have type 1 diabetes mellitus [+6]

Status: Not yet recruiting

A Study of RAY1225 in Participants With Type 2 Diabetes Not Controlled With Diet and Exercise Alone

The goal for this study is to evaluate the efficacy and safety of RAY1225 versus placebo in participants with type 2 diabetes not under control with diet and exercise alone.

Participants needed: 350
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Guangdong Raynovent Biotech Co., LtdUpdated: Aug 24, 2025Locations: 1
Eligibility criteria

Have been diagnosed with type 2 diabetes mellitus (T2DM) [+3]

Have type 1 diabetes mellitus [+6]

Status: Recruiting

Evaluation of RAY1225 in Adult Participants Who Have Obesity or Are Overweight

The primary objective of this study is to demonstrate that RAY1225 is superior to placebo for percent change in body weight.

Participants needed: 640
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Guangdong Raynovent Biotech Co., LtdUpdated: Jul 17, 2025Locations: 1
Eligibility criteria

Age ≥ 18 years. [+2]

Obesity known to be caused by monogenic mutations, other diseases, or medication... [+5]

Status: Recruiting

A Study of RAY1225 in Participants With Impaired Liver Function

The purpose of this study is to assess how fast RAY1225 gets into the blood stream and how long it takes the body to remove it in participants with impaired liver function compared to healthy participants.

Participants needed: 24
Trial details
Phase: Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: Guangdong Raynovent Biotech Co., LtdUpdated: Mar 19, 2025Locations: 1
Eligibility criteria

Participant must be ≥ 18 to ≤ 75 years; [+6]

Participants with an allergic disposition (multiple drug and food allergies) or... [+9]

Status: Recruiting

A Study of RAY1225 in Participants With Obesity

The main purpose of this study is to learn more about the Tolerability of RAY1225 in participants with Obesity. The study will also explore the efficacy of RAY1225. The study will last about six months for each participant.

Participants needed: 270
Trial details
Phase: Phase 2Age: 18-70Biological sex: AllType: InterventionalSponsor: Guangdong Raynovent Biotech Co., LtdUpdated: Mar 19, 2025Locations: 1
Eligibility criteria

Have a body mass index (BMI) of ≥28 kilogram per square meter (kg/m²) or ≥24 kg/... [+1]

Obesity induced by other endocrinologic disorders or monogenetic or syndromic fo... [+5]