Clinical trials

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Condition / disease
Location
Status: Recruiting

Oral Changes With Caloric and no Caloric Sweeteners

The objective of this clinical trial is to compare the effect that the intake of beverages without sweeteners, added with non-caloric sweeteners (stevioside) and caloric sweeteners (sucrose) on oral pH and dental biofilm microbiome in Mexican adolescents. Participants will drink on different occasions a beverage without sweetener, a beverage added with stevioside or a beverage added with sucrose. The researchers will compare the changes that each one causes in salivary pH, dental biofilm pH, dental biofilm bacterial proliferation and dental biofilm microbiome.

Participants needed: 52
Trial details
Phase: Phase 1, Phase 2Age: 12-18Biological sex: AllType: InterventionalSponsor: Hospital Infantil de Mexico Federico GomezUpdated: Oct 9, 2025Locations: 1
Eligibility criteria

Habitual consumption of soft drinks [+4]

Orthodontic treatment [+5]