Status: Recruiting
SUCCESS Score Validation in Fuchs Dystrophy
This prospective multicenter diagnostic study aims to externally validate and extend the SUCCESS Score for predicting the need for endothelial keratoplasty after cataract surgery in patients with Fuchs endothelial corneal dystrophy (FECD). The model's performance and clinical utility are assessed using discrimination, calibration, and reclassification metrics.
Participants needed: 250
Trial details
Age: 40+Biological sex: AllType: ObservationalSponsor: Instituto Ramón y Cajal de Investigación SanitariaUpdated: Dec 4, 2025Locations: 1Duration: 5 Years
Eligibility criteria
Adults aged ≥40 years. [+4]
Epithelial or stromal edema precluding reliable corneal imaging. [+3]