Clinical trials

15

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Motivational Interviewing on Loneliness Level, Activities of Daily Living, and Quality of Life in Elderly

To examine the effects of motivational interviewing on loneliness levels, activities of daily living, and quality of life among older adults living alone

Participants needed: 60
Trial details
Age: 65+Biological sex: AllType: InterventionalSponsor: Karadeniz Technical UniversityUpdated: Apr 13, 2026Locations: 1
Eligibility criteria

being 65 years of age or older, [+4]

having a diagnosis of severe cognitive impairment or dementia, [+2]

Status: Recruiting

Anthropometric Predictability of Full-Thickness Peroneus Longus and Semitendinosus Autograft Size

The study is aimed to determine correlation between autografts used in anterior cruciate ligaments and anthropometric variables e.g. height, sex, weight, BMI etc..

Participants needed: 180
Trial details
Age: 18-45Biological sex: AllType: ObservationalSponsor: Karadeniz Technical UniversityUpdated: Mar 19, 2026Locations: 1Duration: 1 Day
Eligibility criteria

Ages between 18-45 years [+3]

Previous surgery history on donor side knee or ankle [+2]

Status: Not yet recruiting

Effect of Standardized Patient Simulation on Nursing Students' Assessment, Diagnosis Skills, and Experiences

This randomized controlled study aims to determine the effect of teaching delivered through standardized patient simulation on nursing students' assessment and nursing diagnosis determination skills, as well as their learning experiences. First-year nursing students will be randomly assigned to intervention and control groups. The intervention group will receive training based on standardized patient simulation, while the control group will receive traditional instruction. Data will be collected using a sociodemographic information form, case-based assessment tools, and measurement instruments designed to evaluate students' perceptions and experiences related to the educational process. Group comparisons will be conducted to evaluate the effectiveness of the simulation-based teaching method.

Participants needed: 60
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Karadeniz Technical UniversityUpdated: Mar 4, 2026
Eligibility criteria

First-year nursing student [+4]

Previously completed the Fundamentals of Nursing II course [+2]

Status: Recruiting

Percussive Massage Therapy and Muscle Architecture

Percussive massage therapy (PMT) is widely used in therapeutic and athletic settings, but its effects on muscle architecture are not yet fully understood. This study aims to examine the acute effects of PMT applied to the plantar flexor muscles on the muscle architecture of the medial and lateral gastrocnemius muscles in healthy adults aged 18 to 30 years. Participants will be randomly assigned to either a PMT group or a control group. Ultrasonographic assessments will be performed before and after the intervention to evaluate muscle thickness, pennation angle, and fascicle length. The findings of this study may help clarify the acute effects of PMT on muscle structure.

Participants needed: 40
Trial details
Age: 18-30Biological sex: AllType: InterventionalSponsor: Karadeniz Technical UniversityUpdated: Jan 26, 2026Locations: 1
Eligibility criteria

Aged between 18 and 30 years

History of any surgical procedure [+7]

Status: Recruiting

Comparison of IV Analgesia, Thoracic Epidural Analgesia, and ESP Block for Chronic Pain After Open Heart Surgery

This prospective observational study aims to compare three routinely used postoperative analgesia techniques in patients undergoing open heart surgery: intravenous analgesia, thoracic epidural analgesia (TEA), and bilateral erector spinae plane block (ESPB). The primary objective is to evaluate the impact of these analgesia modalities on the development of chronic postoperative pain at 3 months. Secondary objectives include assessing postoperative acute pain scores, additional analgesic requirements, extubation time, mobilization time, intensive care unit stay, hospital stay, respiratory complications, and the relationship between acute and chronic pain. No intervention is assigned by protocol, and all analgesia methods are applied as part of routine clinical practice.

Participants needed: 90
Trial details
Age: 18-85Biological sex: AllType: ObservationalSponsor: Karadeniz Technical UniversityUpdated: Dec 2, 2025Locations: 1
Eligibility criteria

Adults aged 18 to 85 years [+5]

Age < 18 or > 85 years [+9]

Status: Not yet recruiting

Analgesic Effectiveness of SPSIPB Versus Thoracic Epidural and Systemic Opioid Analgesia After VATS (SPSIPB-VATS)

This prospective observational study aims to compare the postoperative analgesic effectiveness of three commonly used pain management strategies in video-assisted thoracoscopic surgery (VATS): Serratus Posterior Superior Intercostal Plane Block (SPSIPB), Thoracic Epidural Analgesia (TEA), and systemic opioid analgesia. The study evaluates postoperative pain scores, opioid consumption, and the need for rescue analgesics within the first 24 hours after surgery. By analyzing analgesic performance and safety profiles of these techniques, the study seeks to provide evidence to guide optimal postoperative pain management for patients undergoing minimally invasive thoracic procedures.

Participants needed: 120
Trial details
Age: 18-75Biological sex: AllType: ObservationalSponsor: Karadeniz Technical UniversityUpdated: Nov 20, 2025Duration: 1 Day
Eligibility criteria

Adults aged 18-75 years [+4]

Known allergy or contraindication to local anesthetics or study medications [+9]

Status: Not yet recruiting

Effect of Abdominal Massage on Patients in Intensive Care Unit

Bowel motility can be affected by many factors such as immobilization, lack of fiber in the nutritional formula, inadequate fluid intake, and lack of privacy for toileting in patients hospitalized in the intensive care unit. Abdominal massage, which is one of the effective methods to increase intestinal motility, is accepted as an intervention that can be safely applied in patients. The aim of our study was to investigate the effect of abdominal massage applied to patients hospitalized in the intensive care unit on sepsis, survival, discharge time from intensive care unit, amount and duration of antibiotic use. Hypotheses H0: Abdominal massage application has no effect on sepsis, survival, discharge time from intensive care unit, amount and duration of antibiotic use in patients hospitalized in intensive care unit. H1: Abdominal massage application has an effect on sepsis, survival, discharge time from intensive care unit, amount and duration of antibiotic use in patients hospitalized in intensive care unit. In this randomized controlled study, the data of patients who received abdominal massage for 5 days during routine physiotherapy applications and those who did not will be recorded. Randomization will be performed in a 1:1 ratio using a computer generated randomization schedule. The effect of abdominal massage on sepsis, survival, discharge time from intensive care, amount and duration of antibiotic use will be examined by using the data of 2 groups with and without abdominal massage in a randomized controlled trial.

Participants needed: 128
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Karadeniz Technical UniversityUpdated: Apr 30, 2025
Eligibility criteria

Patients aged between 18 to 80 years [+4]

History of abdominal surgery [+2]

Status: Not yet recruiting

Transcutaneous Diaphragm Stimulation in ICU Patients

The aim of this study is to compare the effects of transcutaneous electrical diaphragm stimulation (TEDS) on diaphragm thickness, duration of mechanical ventilation, length of ICU stay, and right/left heart functions between patient groups with low and high ejection fraction (EF) levels. This randomized controlled trial will record demographic data, diaphragm ultrasound measurements, and echocardiographic findings of patients who receive or do not receive TEDS for five consecutive days. Participants will be divided into four groups according to their EF levels and whether or not they receive diaphragm stimulation: Group 1: Patients with low EF who receive TEDS Group 2: Patients with high EF who receive TEDS Group 3: Patients with low EF who do not receive TEDS Group 4: Patients with high EF who do not receive TEDS Diaphragm thickness and echocardiographic assessments will be performed at baseline and at the end of the five-day TEDS intervention. TEDS Application Protocol In the ICU, TEDS is administered by a physiotherapist once daily for 20 minutes, five days a week, as part of the routine treatment protocol. The stimulation is delivered using the LGT-231 model device from the LONGEST brand. A transcutaneous current with a frequency of 30-50 Hz and a pulse width of 300-400 microseconds is applied to the diaphragm. The stimulation intensity is increased until visible muscle contraction is achieved. Electrode placement involves: The first pair of electrodes placed bilaterally between the 8th and 10th anterior intercostal spaces, lateral to the xiphoid process. The second pair placed along the mid-axillary line of the thorax, also between the 8th and 10th intercostal spaces.

Participants needed: 76
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Karadeniz Technical UniversityUpdated: Apr 27, 2025
Eligibility criteria

Patients aged between 18 and 80 years [+1]

Presence of known neuromuscular diseases that contraindicate the use of transcut... [+2]

Status: Recruiting

Effect of Progressive Neck Motor Control Exercises on Temporomandibular Joint Dysfunction

The primary aim of this study was to investigate the effects of progressive neck motor control exercises on craniocervical pain, posture, function and kinesiophobia in different types of temporomandibular dysfunction. The secondary aim of the study was to examine the differences between the effects of progressive neck motor control exercises on different types of temporomandibular dysfunction.

Participants needed: 75
Trial details
Age: 18-55Biological sex: AllType: InterventionalSponsor: Karadeniz Technical UniversityUpdated: Jan 29, 2025Locations: 1
Eligibility criteria

18 to 55 years old, [+3]

Cognitive problems, [+9]

Status: Recruiting

Temporomandibular Joint Function, Oral Habits and Pain Complaints of Pregnant Women

The aim of this study is to examine the temporomandibular joint functions, oral habits and pain complaints of pregnant women. .

Participants needed: 224
Trial details
Age: 18-45Biological sex: FemaleType: ObservationalSponsor: Karadeniz Technical UniversityUpdated: Jan 7, 2025Locations: 1Duration: 1 Day
Eligibility criteria

Being between the ages of 18-45, [+5]

Those with any systemic disease concerning the musculoskeletal system, [+12]

Status: Recruiting

Effect of Informing Family Members of Patients During Surgery

Psychological and physiological issues encountered by family members due to the intraoperative process are factors that complicate the support and care systems of the patient. It is stated that family members of patients undergoing surgery, especially those who do not have sufficient information about the surgical process, experience stress, anxiety, and concern. The need for nursing interventions aimed at providing information about the surgical process, reducing the anxiety levels of family members during the surgery, and supporting them is emphasized. In this context, the study aims to evaluate the effect of periodically informing family members of patients undergoing abdominal cancer surgery via phone during the surgery on their anxiety levels.

Participants needed: 104
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Karadeniz Technical UniversityUpdated: Dec 9, 2024Locations: 1
Eligibility criteria

Being a first-degree relative who has given consent, [+5]

Having a hearing or speech impairment, [+3]

Status: Recruiting

The Effect of Patient Safety Escape Room on Nursing Students' Knowledge Level and Team Collaboration

The concept of patient safety first emerged more than two decades ago in research by practitioners applying different approaches to improve care in the areas they work in. The main goal in patient safety is to prevent mistakes while providing service, to protect patients from possible harm and to minimize the possibility of making mistakes. For this reason, patient safety is one of the indispensable parts of nursing education. The planned research will be carried out in order to increase the patient safety escape room design and the current knowledge level of student nurses and team cooperation on this subject. The research will be carried out with the first year students of the Faculty of Health Sciences, Nursing Department of a state university, in an experimental design with pre-test and post-test. The data of the research will be collected with the "General Information Questionnaire", "Patient Safety Knowledge Test", "Collaboration Scale" and "Gamy Experience for Gamification Scale". It is planned to carry out the study with 60 students. Control Group=30, Experiment Group=30. After the subject of patient safety is explained in the Nursing Fundamentals course, the students who agree to participate in the study will be randomly divided into experimental and control groups. Patient safety practices will be explained to the control and experimental group students with the demonstration method in the laboratory environment after the lesson. Experimental group students will be taken to patient safety escape rooms prepared by the researcher. Students will be taken to escape rooms in groups of 5 and will be expected to perform the targeted tasks. After the lab and escape room activity, students will fill in the knowledge test and scales again. Since there is a limited number of studies in the literature on the knowledge levels of nursing students on patient safety and team collaboration, and there is no study in which escape room design is used in the field of nursing in Turkey, the research is important in terms of filling this gap in the literature.

Participants needed: 60
Trial details
Biological sex: AllType: InterventionalSponsor: Karadeniz Technical UniversityUpdated: Sep 23, 2024Locations: 1
Eligibility criteria

Being a first year nursing student, [+3]

Not attending the theoretical lecture on Patient Safety [+5]

Status: Not yet recruiting

Arteriovenous Fistula Cannulation Pain and Skin Cooling Device

To determine the effect of the antistress ball, valsalva maneuver and skin cooling device, which are one of the nonpharmacological methods applied to hemodialysis patients, on the level of pain and fear of pain due to arteriovenous fistula cannulation.

Participants needed: 60
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Karadeniz Technical UniversityUpdated: Sep 19, 2024Locations: 1
Eligibility criteria

be 18 years of age or older [+8]

being under the age of 18 [+10]

Status: Not yet recruiting

IR Beam Used Before Peripheral Intravenous Catheter Application on Vein Visibility

The study will be conducted in the Oncology and Cardiovascular Surgery (CVS) services of a university hospital. In the research, 30 patients will constitute the control group and 30 patients will constitute the experimental group. A nurse working in the clinics where the study will be conducted will perform the PIVK procedure, and we will randomly select the control and experimental groups and apply light to the area where the PIVK will be applied to the patients in the experimental groups with a flashlight that emits infrared rays for 10 minutes. The nurse will not be aware of whether the radiation application was made to the patient or not. The veins will be evaluated by the nurse performing PIVK. We will fill out the necessary forms in ANNEX 1 (control group) and APPENDIX 2 (experimental group) while the PIVK procedure is applied. After the procedure is completed, the patient's pain, anxiety and satisfaction level during the procedure will be marked. The data will be entered into the SPSS program and evaluated with statistical tests. According to the results, the effect of IR rays used before PIVK application on the patient's pain, anxiety and satisfaction and on the procedure time spent by the nurse for the application will be determined.

Participants needed: 60
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: Karadeniz Technical UniversityUpdated: Aug 23, 2024Locations: 3
Eligibility criteria

PIVK will be inserted, [+6]

Sudden movements during PICK insertion, [+1]

Status: Not yet recruiting

Developing a Simulation for Parenteral Drug Administration

In the current Covid-19 pandemic process, distance education has become widespread and will continue to become widespread in the return to normal. In the distance education process, theoretical courses can be given with methods such as synchronous or asynchronous lectures, questions and answers, and discussion. However, in departments such as the nursing department, where laboratory and clinical practice are given during the term, there are some difficulties in providing the practice with distance education. Since students cannot be in clinical practice, they cannot develop their basic nursing skills. However, it is not possible for students to develop their skills in distance education. In addition, due to the high number of students in face-to-face teaching and the low number of lecturers, the lecturer and students cannot spend enough and effective time in the laboratories. Because there are 50-60 students per lecturer and therefore students are not sufficient in basic nursing skills. In order for students to improve their skills, there are technological methods that allow students to try the application on their own, at the desired place and time, without risking patient safety, in virtual environments, without entering the laboratory. Simulation opportunities can be provided to students by creating environments, models, materials and patients similar to the real hospital environment in virtual environments. It is seen in the literature that similar studies have been carried out outside of our country and are used in nursing education. However, in our country, a similar application was made in the virtual environment only in the thesis study of the director. This thesis study, which is similar to this project study, only includes tracheostomy care skill, which is one of the basic nursing skills. This project will include simulation parenteral drug administration skills in our work. For this reason, it will be the first simulation prepared for parenteral drug applications in our country. Drug administration constitutes an important step in patient safety. Although this section is explained theoretically, students are not given sufficient opportunities to have different drug doses prepared and administered in the laboratory. For this reason, when the student encounters a complex situation in the clinic, the decision-making process is prolonged and the risk of making mistakes increases.

Participants needed: 128
Trial details
Age: 18-25Biological sex: AllType: InterventionalSponsor: Karadeniz Technical UniversityUpdated: Jun 25, 2024Locations: 1
Eligibility criteria

Those who have registered for the Fundamentals of Nursing II Course for the firs... [+3]

Having graduated from Health Vocational High School or studied a health-related... [+1]