Status: Recruiting
Extracellular Vesicles for Rejection Monitoring in Cardiac Transplantation
This study will analyze extracellular vesicle (EV)-derived protein profiles in heart transplantated patients during the first 15 months post-transplantation to investigate, if there are distinct EV-derived proteins or protein patterns that allow early and reliable diagnosis of acute cardiac allograft rejection. Additionally, it will explore temporal changes in the EV-derived protein profile during the early postoperative period irrespective of acute allograft rejection, and will investigate, if there are correlations between EV protein markers and imaging findings.
Participants needed: 30
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Laurenz Kopp FernandesUpdated: Jul 1, 2026Locations: 1
Eligibility criteria
Subject is either on the heart transplant waiting list or is still hospitalised... [+6]
Concurrent multiple solid organ or tissue transplants. [+6]