Clinical trials

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Condition / disease
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Status: Not yet recruiting

Electroacupuncture for Generalized Anxiety Disorder: Clinical Efficacy and Neuroimaging Mechanisms

This study aims to evaluate the clinical efficacy and safety of electroacupuncture (EA) in treating Generalized Anxiety Disorder (GAD). Participants will be randomly assigned to an EA group, a sham EA group, or a waiting-list control group. All participants will continue their routine medication (Paroxetine). The primary goal is to observe the reduction in anxiety symptoms using the Hamilton Anxiety Scale (HAMA). Additionally, the study will use functional MRI (fMRI) and Magnetic Resonance Spectroscopy (MRS) to explore the brain mechanisms through which EA helps alleviate anxiety.

Participants needed: 123
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: Lishu GaoUpdated: Feb 6, 2026
Eligibility criteria

Meet the DSM-5 diagnostic criteria for Generalized Anxiety Disorder (GAD). [+5]

Complicated with severe cardiovascular, cerebrovascular, or organic diseases. [+3]