Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Lifestyle Interventions to Prevent cOgnitive Deficits in Subjects With Depressive Symptoms: From mEchanisms to Clinical pRactice

POWER project is a randomized, controlled, non-profit study with the primary objective of testing the effectiveness of non-pharmacological interventions-such as physical activity, cognitive training, and dietary supplementation-in reducing depressive symptoms and preventing or delaying cognitive impairments that frequently co-occur in individuals with Major Depressive Disorder (MDD).

Participants needed: 120
Trial details
Age: 50-80Biological sex: AllType: InterventionalSponsor: National Science and Technology Council, TaiwanUpdated: Jun 17, 2026Locations: 1
Eligibility criteria

Aged 50-80 years old [+2]

Status: Recruiting

Integrating Digital Phenotypes and AI-Driven Cognitive-Behavioral Therapy: Advancing Precision Medicine in Depression Through Digital Medicine

This project aims to integrate digital phenotyping and AI-driven iCBT into a comprehensive platform for MDD diagnosis and treatment in Taiwan. The study will explore dynamic, real-time behavioral and physiological markers to refine diagnostic classifications and optimize personalized therapeutic strategies.

Participants needed: 100
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: National Science and Technology Council, TaiwanUpdated: Mar 30, 2026Locations: 1
Eligibility criteria

(1) Aged 18-75 years [+4]

Scores of 5 ( Markedly ill), 6,(Severely ill), and 7 (Among the most extremely i... [+2]

Status: Recruiting

NUTRIMOOD-Inflammation and Depressive Comorbidity in Obesity: Modulation by Omega-3 Polyunsaturated Fatty Acids Status

A 12-week, randomized, placebo-controlled trial testing the efficacy of n-3 PUFA treatment (EPA, 2 g/day) in alleviating depressive symptoms in a subgroup of obese subjects with comorbid depression and low n-3 PUFA status (n-3 index \< 8%) (81), from the Taiwanese cohort. Associations with PLA2/COX2 genotypes, lifestyle, nutritional profiles and gut microbiota will also be determined.

Participants needed: 50
Trial details
Age: 18-54Biological sex: AllType: InterventionalSponsor: National Science and Technology Council, TaiwanUpdated: Feb 27, 2026Locations: 1
Eligibility criteria

Major depressive disorder. [+1]

Schizophrenia [+7]