Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

The Safety/Efficacy Study of Human Umbilical Cord Mesenchymal Stem Cells Therapy (19#iSCLife®-LDP) for Lumbar Discogenic Pain

This experimental use umbilical cord mesenchymal stem cells in treatment of the early stage of lumbar discogenic pain (endogenous pain of the disc) to evaluate its safety and efficacy. This experimental is mainly aimed at over 18years old people, regardless of gender, with refractory and persistent back pain for more than 6 months. The efficacy and safety of mesenchymal stem cells (MSCS) were evaluated by low-temperature plasma ablation and intravertebral disc injection, which were divided into treatment group and control group.

Participants needed: 242
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Sclnow Biotechnology Co., Ltd.Updated: Apr 23, 2026Locations: 1
Eligibility criteria

age over 18 [+5]

coagulation dysfunction or anticoagulant therapy; [+10]

Status: Recruiting

hUC Mesenchymal Stem Cells (19#iSCLife®-LC) in the Treatment of Decompensated Hepatitis b Cirrhosishepatitis b Cirrhosis

1. Evaluation the safety of using human umbilical mesenchymal stem cells to treat patients with hepatitis B cirrhosis. 2. Observe the curative effect of patients with hepatitis B cirrhosis who use human umbilical mesenchymal stem cells to treat. 3. Explore the possible mechanism of human umbilical mesenchymal stem cells to treat patients with hepatitis B cirrhosis.

Participants needed: 20
Trial details
Phase: Phase 1Age: 18-60Biological sex: AllType: InterventionalSponsor: Sclnow Biotechnology Co., Ltd.Updated: Apr 23, 2026Locations: 1
Eligibility criteria

Age 18-60 years old, gender not limited, body mass index (BMI) between 19-25 kg/... [+3]

Insufficiency of vital organs, such as heart, kidney and lung; [+7]

Status: Not yet recruiting

Umbilical Cord Mesenchymal Stem Cells Therapy (19#iSCLife®-SA) for Patients With Spinocerebellar Ataxia

The purpose of this study is verify the safety and efficacy of Human Umbilical Cord Mesenchymal Stem Cells (UC-MSC) therapy for patients with Spinocerebellar Ataxia, and in addition, explore the possible mechanisms of UC-MSC therapy in Spinocerebellar Ataxia.

Participants needed: 45
Trial details
Phase: Phase 2Age: 16-60Biological sex: AllType: InterventionalSponsor: Sclnow Biotechnology Co., Ltd.Updated: Apr 23, 2026
Eligibility criteria

Clinical and genomic test diagnoses as spinocerebellar ataxias (SCA) (include SC... [+2]

Cardiac, renal, hepatic insufficiency; total bilirubin is 1.5 times higher than... [+10]

Status: Recruiting

The Safety/Efficacy of hUC Mesenchymal Stem Cells(19#iSCLife®-OA) Therapy for Patients With Osteoarthritis

The purpose of this study is verify the efficacy and safety of Human Umbilical Cord Mesenchymal Stem Cells (UC-MSC) therapy for patients with Osteoarthritis, and in addition, provide basis for exploring the treatment regimen of UC-MSC therapy in different degree of cartilage defect disease

Participants needed: 60
Trial details
Phase: Phase 2Age: Up to 70Biological sex: AllType: InterventionalSponsor: Sclnow Biotechnology Co., Ltd.Updated: Dec 4, 2025Locations: 1
Eligibility criteria

Diagnosis of Knee Osteoarthritis by Kellgren and Lawrence Grading Scale, classif... [+6]

Refuse to sign the consent form, or cannot keep follow-up visit [+17]