Clinical trials

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Condition / disease
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Status: Not yet recruiting

EFFICACY OF TRANSMUCOSAL MINIPLEITE STABILIZATION TECHNIQUE VERSUS INTRA-ARCH WIRE STABILIZATION TECHNIQUE FOR FIXATION OF SAGITTAL & PARA-SAGITTAL TYPES OF PALATAL FRACTURES IN TERMS OF INTRA-ARCH MOLAR DISTANCE & MAXILLO-MANDIBULAR MOLAR RELATION

The purpose of this study is to reduce uncertainity around decision making regarding use of transmucosal miniplate stabilization technique in place of intra-arch wire stabilization technique to get better outcomes. It will help establish future guidelines for sagittal and para-sagittal types of palatal fracture treatment Under general anasthesia wires will be passed between molars of both sides for palatal fracture reduction or fracture will be reduced by applying plate at fracture site

Participants needed: 40
Trial details
Age: 16+Biological sex: AllType: InterventionalSponsor: Services Institute of Medical Sciences, PakistanUpdated: Dec 10, 2025Locations: 1
Eligibility criteria

• Age ≥16 years [+3]

• Transverse or comminuted palatal fractures [+3]

Status: Not yet recruiting

Comparison of Curcumin and Intralesional Steroids in Oral Submucous Fibrosis

The goal of this clinical trial is to learn if Curcumin is better than Intralesional Steroid Injection for the treatment of oral submucous fibrosis. The main question it aims to answers are: 1. If Curcumin is more effective to improve burning sensation as compared to Intralesional steroid. 2. Does Curcumin treatment results in better mouth opening versus Intralesional steroid. 3. Can Curcumin helps to improve tongue protrusion as compared to Intralesional steroids. Participants will be: * Assessed for one month, two month and three month. * Burning Sensation will be assessed with visual analogue scale (VAS). * Mouth Opening will be measured in mm with ruler. * Tongue Protrusion will be assessed with the visual analogue scale (VAS).

Participants needed: 70
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Services Institute of Medical Sciences, PakistanUpdated: Mar 6, 2025Locations: 1
Eligibility criteria

Patients diagnosed with Oral submucous fibrosis in accordance with operational d... [+1]

Patient unable to quit the habit of gutkha, tobacco & betel nut chewing [+5]

Status: Not yet recruiting

Intraosseous Versus Submucosal Dexamethsone Injection in Third Molar Surgery

The goal of this clinical trial is to learn if intraosseous dexamethasone injection is better for pain and swelling postop 3rd molar surgery than submucosal dexamethasone injection. The main questions it aims to answer are: Does intraosseous dexamethasone injection provide better pain relief and lessen facial swelling than submucosal dexamethasone injection Does intraosseous dexamethasone injection provide better interincisal opening than submucosal dexamethasone injection Researcher will compare both the techniques to see if intraosseous dexamethasone injection works better than submucosal dexamethasone injection Participants will: Be assessed at 3rd and 7th day postoperatively Pain will be assessed through visual analog scale score Facial measurement will be calculated as horizontal measurement plus vertical measurement divided by 2, where horizontal measurement will be taken as the distance between corner of the mouth and the earlobe attachment, and vertical measurement will be taken as distance from outer canthus of the eye to the angle of jaw. Interincisal opening will be measured from the incisal edge of the maxillary central incisors to the incisal edge of mandibular central incisors at the midline by using millimeter ruler

Participants needed: 76
Trial details
Age: 18-35Biological sex: AllType: InterventionalSponsor: Services Institute of Medical Sciences, PakistanUpdated: Dec 13, 2024Locations: 1
Eligibility criteria

Patients undergoing mandibular third molar surgery [+2]

Uncontrolled systemic medical problems including diabetes and hypertension [+6]

Status: Not yet recruiting

Efficacy of Transoral Versus Transbuccal Technique for Fixation of Mandibular Angle Fracture

The goal of this clinical trial is to learn if transbuccal technique for mandibular angle fracture is better than transoral technique. The main questions it aims to answer are: * Does transbuccal technique provide better mouth opening than transoral technique * Radiographic gap and displacement between fracture lines is more prevalent in transoral technique than transbuccal technique postoperatively Researcher will compare both the techniques to see if transbuccal technique works better than transoral technique Participants will: * Be assessed 1 week , 1 month and 3 months postoperatively * Their mouth opening will be assessed by measuring interincisal opening with ruler * Radiographic gap between fracture segments and displacement of fractured segments will be measured on OPG through ruler

Participants needed: 68
Trial details
Age: 16-70Biological sex: AllType: InterventionalSponsor: Services Institute of Medical Sciences, PakistanUpdated: Oct 9, 2024Locations: 1
Eligibility criteria

1.All dentate and partially dentate patients with unilateral mandibular angle fr... [+1]

1.Comminuted mandibular angle fractures. [+3]