Clinical trials

15

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Condition / disease
Location
Status: Recruiting

Evaluation of the First, Second, and New Drug-Eluting Stents in Routine Clinical Practice

The objective of this study is to evaluate effectiveness and safety of the new drug-eluting stent (DES), as compared with the first-,second-,third-, and fourth-generation DES, in the "real world" daily practice.

Participants needed: 50,000
Trial details
Age: 19+Biological sex: AllType: ObservationalSponsor: Seung-Jung ParkUpdated: Jun 30, 2026Locations: 1
Eligibility criteria

coronary disease amenable to percutaneous coronary intervention (PCI) [+1]

patients with a mixture of several DES [+2]

Status: Recruiting

The DECISION-CTO Extended 10 Y Follow-up

The goal of this clinical trial is to compare long term efficacy of drug-eluting stent implantation compare to optimal medical treatment in patient with chronic total occlusion in a very long-term follow-up (minimum 10 years) period.

Participants needed: 840
Trial details
Age: 19+Biological sex: AllType: ObservationalSponsor: Seung-Jung ParkUpdated: Jun 24, 2026Locations: 19
Eligibility criteria

Clinical 1) Patients with angina or silent ischemia and documented ischemia 2) P... [+6]

History of bleeding diathesis or coagulopathy [+13]

Status: Recruiting

IRIS-Coroflex NEO Cohort

The objective of this study is to evaluate the effectiveness and safety of Coroflex ISAR NEO stents in comparison to other drug-eluting stents (DES) in real-world practice.

Participants needed: 1,000
Trial details
Age: 19+Biological sex: AllType: ObservationalSponsor: Seung-Jung ParkUpdated: Jun 25, 2026Locations: 11Duration: 5 Years
Eligibility criteria

Patients ≥ 19 years old [+2]

Patients with a mixture of other DESs [+2]

Status: Recruiting

Fractional Flow Reserve Versus Angiography for Treatment-Decision and Evaluation of Significant Left MAIN Coronary Artery Disease

The primary purpose of the study was to determine whether the 2-year probability of major adverse cardiac events (primary composite outcome) differed significantly between patients who underwent angiography-guided Percutaneous Coronary Intervention(PCI) and those who underwent Fractional Flow Reserve(FFR)-guided PCI in patients with Left Main Coronary Artery disease(LMCA).

Participants needed: 960
Trial details
Age: 20+Biological sex: AllType: InterventionalSponsor: Seung-Jung ParkUpdated: Jun 24, 2026Locations: 49
Eligibility criteria

The subject must be ≥20 years of age with angina and/or evidence of myocardial i... [+2]

left anterior descending coronary artery (LAD) or left circumflex coronary arter... [+15]

Status: Recruiting

IRIS- DESyne X2 in the IRIS-DES Registry

This study evaluates effectiveness and safety of DESyne X2 in Routine Clinical Practice.

Participants needed: 1,000
Trial details
Age: 19+Biological sex: AllType: ObservationalSponsor: Seung-Jung ParkUpdated: Jun 24, 2026Locations: 6
Eligibility criteria

Age 19 and more [+2]

Intervention with DeSyne X2 drug-eluting coronary stent and other drug eluting s... [+2]

Status: Not yet recruiting

PREventive Invasive Strategy for Obstructive Coronary Artery Disease With Vulnerable Plaque Evaluated by CoroNary Computed Tomography Angiography-2

The PREVENT-2 trial is to determine whether an initial invasive strategy-consisting of early coronary angiography (CAG) with intent for preventive percutaneous coronary intervention (PCI) in addition to optimal medical therapy (OMT)-reduces the incidence of the primary composite outcome of cardiac death, target-vessel myocardial infarction (MI), unplanned urgent revascularization, or hospitalization for unstable or progressive angina at 3 years, compared with an initial conservative strategy of optimal medical therapy (OMT) alone, in patients with high-risk vulnerable plaque identified by coronary computed tomography angiography (CCTA).

Participants needed: 2,500
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Seung-Jung ParkUpdated: May 11, 2026Locations: 1
Eligibility criteria

Patients aged ≥18 years [+6]

Acute coronary syndrome (ACS) requiring urgent or emergent invasive evaluation [+14]

Status: Recruiting

Study of the Natural History of FFR Guided Percutaneous Coronary Intervention

About 20,000 patients with FFR (Fractional Flow Reserve) will be enrolled and evaluated for the natural history of coronary lesions at 2 years clinical and imaging follow-up.

Participants needed: 20,000
Trial details
Age: 35+Biological sex: AllType: ObservationalSponsor: Seung-Jung ParkUpdated: Mar 20, 2026Locations: 29
Eligibility criteria

Age 35 years and older [+2]

Stenosis with TIMI<3 flow [+9]

Status: Recruiting

Observational Study for Left Main Disease Treatment

The purpose of this study is to observe clinical courses for long-term in patients with unprotected LMCA disease and to evaluate comparative results of medical treatment, coronary stenting with drug-eluting stents, and CABG for the treatment of an unprotected LMCA stenosis in the "real world" daily practice.

Participants needed: 10,000
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Seung-Jung ParkUpdated: Mar 20, 2026Locations: 42
Eligibility criteria

Significant unprotected left main stenosis (>50% by visual estimation) [+4]

Protected left main stenosis

Status: Recruiting

Evaluation of Effectiveness and Safety of Xience Skypoint Stents in Routine Clinical Practice

The objective of this study is to evaluate the effectiveness and safety of XIENCE Skypoint stents in comparison to other drug-eluting stents (DES) in real-world practice.

Participants needed: 2,000
Trial details
Age: 19+Biological sex: AllType: ObservationalSponsor: Seung-Jung ParkUpdated: Jan 2, 2026Locations: 1
Eligibility criteria

Patients ≥ 19 years old [+2]

Patients with a mixture of other DESs [+2]

Status: Recruiting

Asan Medical Center Myocardial Infarction Registry

This study evaluates long-term outcome of patients diagnosed as acute myocardial infarction and treated with medication, coronary artery bypass surgery and percutaneous coronary intervention in Asan medical center, Korea.

Participants needed: 5,000
Trial details
Age: 19+Biological sex: AllType: ObservationalSponsor: Seung-Jung ParkUpdated: Jan 2, 2026Locations: 1
Eligibility criteria

All consecutive acute myocardial infarction patients diagnosed through coronary...

Status: Recruiting

Prognosis of Coronary Stenosis Based on Intracoronary Imaging; A Multicenter, Prospective Observational Study

The purpose of this study is to evaluate the prognosis of coronary stenosis based on intracoronary Imaging.

Participants needed: 4,000
Trial details
Age: 19+Biological sex: AllType: ObservationalSponsor: Seung-Jung ParkUpdated: Jan 2, 2026Locations: 15
Eligibility criteria

Patients with intracoronary imaging [+1]

Severe calcification and/or severe tortuosity [+5]

Status: Recruiting

Asan Multivessel Registry

The purpose of this study is to evaluate long-term prognoses of patients with multivessel coronary disease treated medically or surgically or percutaneously in real world practice.

Participants needed: 25,000
Trial details
Age: 19+Biological sex: AllType: ObservationalSponsor: Seung-Jung ParkUpdated: Jan 2, 2026Locations: 1
Eligibility criteria

Patients with multivessel disease from 1995 in Asan Medical Center [+1]

For prospective cohort, not agreeing to participate with written informed consen...

Status: Recruiting

Prospective Evaluation of Drug-Eluting Stents in Routine Clinical Practice (ASAN PCI Registry)

The objective of this study is to evaluate effectiveness and safety of drug-eluting stent implantation in the "real world" daily practice.

Participants needed: 50,000
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Seung-Jung ParkUpdated: Jan 2, 2026Locations: 1Duration: 1 Year
Eligibility criteria

coronary disease amenable to percutaneous coronary intervention (PCI) [+1]

patients with a mixture of several drug eluting stents [+2]

Status: Recruiting

Drug-Eluting Balloon Registry in Routine Clinical Practice

The purpose of this study is to evaluate long-term effectiveness and safety of patients with coronary disease treated with drug eluting balloon in real world practice.

Participants needed: 1,500
Trial details
Age: 20+Biological sex: AllType: ObservationalSponsor: Seung-Jung ParkUpdated: Dec 29, 2025Locations: 9
Eligibility criteria

After pre dilatation residual stenosis 30% and less and also without vessel diss... [+3]

Allergy to paclitaxel, antiplatelet [+2]