Clinical trials

This study aims to investigate the effects of low-intensity blood flow restriction training (LI-BFRT) on lower-limb strength and kicking performance in taekwondo athletes. Blood flow restriction training is a method that partially restricts blood flow to the muscles during exercise, which may improve performance while reducing training load.

The goal of this clinical trial is to learn if home-based temporal interference stimulation (TIS) works to improve motor symptoms in people with Parkinson's disease (PD). It will also learn about the safety of this treatment. The main questions it aims to answer are: 1. Does home-based TIS improve movement problems such as slow movement, stiffness, and walking difficulty? 2. Are the effects maintained after the treatment ends? 3. What medical problems (adverse events) occur during treatment? Researchers will compare active TIS to a sham treatment (a look-alike procedure that does not deliver active stimulation) to see if TIS works. Participants will: 1. Receive active TIS or sham stimulation once a day for 4 weeks at home under remote supervision 2. Visit the clinic at specific time points for movement assessments 3. Complete online questionnaires about symptoms and quality of life

The goal of this clinical trial is to learn how different running environments affect physiological responses, emotional regulation, exercise motivation, and attentional control in healthy college students. The main questions it aims to answer are: How do different running environments (indoor treadmill, outdoor road, and outdoor grass) affect physiological stress and recovery, such as heart rate variability, blood pressure, cortisol, and blood lactate levels? Are there differences in subjective emotional experiences, perceived recovery, and exercise motivation when running in natural versus artificial environments? Does the running environment influence post-exercise cognitive performance, specifically inhibitory control and sustained attention? Researchers will compare indoor treadmill running, outdoor road running, and outdoor grass running to see if natural environments provide greater benefits for stress relief, mood improvement, and cognitive enhancement. Participants will: Attend three separate 70-minute experimental sessions (one for each environment) with at least 48 hours between sessions. Complete baseline physiological measurements (HRV, blood pressure, saliva, and blood samples), psychological questionnaires, and computerized cognitive tasks. Complete a 30-minute moderate-intensity running session in the randomly assigned environment while wearing a heart rate monitor. Repeat the physiological measurements, psychological questionnaires, and cognitive tasks immediately and 10 minutes after the running session.

The goal of this clinical trial utilizing a randomized crossover design)is to explore the modulating effects of different exercise environments （green parks, outdoor athletic tracks, and indoor settings) on acute responses to High-Intensity Interval Training (HIIT). It aims to determine if environmental factors can optimize an individual's stress regulation, cognitive improvement, and psychological exercise experience. The study involves 25 healthy full-time college students aged 18 to 25. The main questions it aims to answer are： 1. Are there significant differences in physiological stress (e.g., salivary cortisol, HRV) and cardiovascular responses when performing HIIT in different exercise environments (indoor, track, park)? 2. How does the exercise environment influence executive function (inhibitory control and cognitive flexibility) and subjective psychological experiences (e.g., emotional state, enjoyment, and exercise motivation) following HIIT? Researchers will compare the performance of participants across three conditions-Green Park (natural environment), Outdoor Athletic Track (conventional outdoor environment), and Indoor Venue (artificial environment)-to identify the modulating effects of different environments on exercise outcomes. Participants will ： Sign the informed consent form and complete baseline health screenings and psychological scales. Undergo resting physiological measurements (Heart Rate, Heart Rate Variability, Blood Pressure, Salivary Cortisol) and complete computerized executive function tasks (Stroop task and More-odd-shifting task). Perform approximately 15 minutes of standardized preparation activities (warm-up). Complete a 15-minute high-intensity interval jump-rope training session (using a protocol of 30 seconds of high-intensity exercise followed by 30 seconds of recovery) in a randomly assigned environment. Immediately following the exercise, undergo repeated physiological measurements, psychological assessments, and cognitive function tests.