Clinical trials

21

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Role of Bumetanide in Treatment of Autism

Role of bumetanide in Autism

Participants needed: 80
Trial details
Phase: Phase 3Age: 3-12Biological sex: AllType: InterventionalSponsor: Sherief Abd-ElsalamUpdated: Feb 23, 2021Locations: 1
Eligibility criteria

All patients with ASD diagnosed by CARS rating Scale⩾30. [+1]

Patients with ASD associated with neurological antecedents (including epilepsies...

Status: Recruiting

Clinical Study Evaluating Beta Blockers Use and Fracture Risk in Patients With Primary Osteoporosis

Clinical study evaluating selective or nonselective beta blockers use and fracture risk in patients with primary osteoporosis

Participants needed: 50
Trial details
Phase: Phase 3Age: 50+Biological sex: AllType: InterventionalSponsor: Sherief Abd-ElsalamUpdated: Jan 12, 2021Locations: 1
Eligibility criteria

• Male & female osteoporotic patient aged ≥ 50 years [+2]

Angiotensin converting enzyme inhibitor (ACEI) or Angiotensin receptor blockers...

Status: Recruiting

Carvedilol Versus Endoscopic Band Ligation for Primary Prophylaxis of Oesophageal Variceal Bleeding

Carvedilol versus endoscopic band ligation for primary prophylaxis of oesophageal variceal bleeding in cirrhotic patients with arterial hypertension

Participants needed: 306
Trial details
Phase: Phase 2, Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Sherief Abd-ElsalamUpdated: Aug 5, 2020Locations: 1
Eligibility criteria

• Aged >18 years [+2]

• History of variceal bleeding or previous primary prevention of varices. [+9]

Status: Recruiting

Efficacy of Nucleo CMP Forte in Traumatic Brain Injury in Pediatrics

Efficacy of Nucleo CMP Forte in Traumatic Brain Injury in Pediatrics

Participants needed: 100
Trial details
Phase: Phase 3Age: Up to 18Biological sex: AllType: InterventionalSponsor: Sherief Abd-ElsalamUpdated: Aug 5, 2020Locations: 1
Eligibility criteria

Children with traumatic brain injury: Moderate and Severe.

Underlying CNS disorders,

Status: Recruiting

Pantoprazole in Cisplatin Nephrotoxicity

Pantoprazole in Cisplatin Nephrotoxicity

Participants needed: 60
Trial details
Phase: Phase 3Biological sex: AllType: InterventionalSponsor: Sherief Abd-ElsalamUpdated: Jan 3, 2020Locations: 1
Eligibility criteria

Patients with head and neck cancer

GFR less than 59. [+2]

Status: Recruiting

Role of Coenzyme Q in ADHD in Children

Role of Coenzyme Q in ADHD in Children

Participants needed: 40
Trial details
Phase: Phase 3Age: 2-18Biological sex: AllType: InterventionalSponsor: Sherief Abd-ElsalamUpdated: Jan 2, 2020Locations: 1
Eligibility criteria

Patients with ADHD

Comorbidities like Autism, Anxiety, Obsessive compulsive disorder.

Status: Recruiting

Role of Point of Care Ultrasound in Endotracheal Tube Placement

Role of point of care ultrasound in endotracheal tube placement in children

Participants needed: 40
Trial details
Age: Up to 18Biological sex: AllType: InterventionalSponsor: Sherief Abd-ElsalamUpdated: Jan 2, 2020Locations: 1
Eligibility criteria

Children below 18 years needing endotracheal intubation.

Age more than 18 years. [+2]

Status: Recruiting

Effect of GABA on ADHD and Seizures in Children With Epilepsy.

Effect of GABA on ADHD and seizures in Children with epilepsy.

Participants needed: 30
Trial details
Phase: Phase 4Age: 4-18Biological sex: AllType: InterventionalSponsor: Sherief Abd-ElsalamUpdated: Oct 30, 2019Locations: 1
Eligibility criteria

Epilepsy [+1]

Epilepsy without ADHD

Status: Recruiting

Study of Orphenadrine' in the Treatment of Muscle Cramps in Patients With Cirrhosis

Muscle cramps are common in patients with liver disease and associated with significantly diminished quality of life. Patients with cirrhosis often experience muscle cramps with varied frequency and severity. The exact mechanisms by which they occur remain unclear, although a number of pathophysiological events unique to liver disease may contribute. Clinical studies have identified alterations in 3 areas: nerve function, energy metabolism, and plasma volume/electrolytes (1) Orphenadrine is an anticholinergic drug with prominent central nervous system (CNS) and peripheral actions used to treat painful muscle spasms and other similar conditions. The combination of anticholinergic effects and CNS penetration make orphenadrine useful for pain of all etiologies, including from: radiculopathy, muscles, and headaches. \[3,4\]

Participants needed: 100
Trial details
Phase: Phase 3Biological sex: AllType: InterventionalSponsor: Sherief Abd-ElsalamUpdated: Jun 7, 2019Locations: 1
Eligibility criteria

Cirrhosis [+1]

• Allergy to orphenadrine [+5]

Status: Recruiting

Citicoline as Neuroprotector in Preterm

Citicoline as neuroprotector in preterm

Participants needed: 40
Trial details
Phase: Phase 3Age: Up to 1Biological sex: AllType: InterventionalSponsor: Sherief Abd-ElsalamUpdated: May 29, 2019Locations: 1
Eligibility criteria

Preterm on CPAP or ventilator

Multiple congenital anomalies

Status: Recruiting

Citicoline as Neuroprotector in Neonates Exposed to Hypoxia

Citicoline as neuroprotector in neonates exposed to hypoxia: A randomized controlled trial

Participants needed: 40
Trial details
Phase: Phase 3Age: Up to 1Biological sex: AllType: InterventionalSponsor: Sherief Abd-ElsalamUpdated: May 29, 2019Locations: 1
Eligibility criteria

neonates with hypoxia.

hypoxic ischemic encephalopathy

Status: Recruiting

Mebendazole as Adjuvant Treatment for Colon Cancer

mebendazole treating colon cancer

Participants needed: 40
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Sherief Abd-ElsalamUpdated: Apr 24, 2019Locations: 1
Eligibility criteria

Colorectal cancer stage 4.

Agranulocytosis [+2]

Status: Recruiting

Impact of P53 and SIRT1 in Type 2 Diabetes

Investigating the impact of p53 and SIRT1 in the development of type 2 DM

Participants needed: 90
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Sherief Abd-ElsalamUpdated: Apr 24, 2019Locations: 1
Eligibility criteria

Prediabetic subjects.

Confirmed diabetes. [+1]

Status: Recruiting

Statins and ARBs on Rheumatoid Activity

Investigational and comparative study between the anti-inflammatory effectof both angiotensin reeptor blockers and statins on rheumatoid arthritis disease activity on Egyptian patients

Participants needed: 45
Trial details
Phase: Phase 3Age: 18-65Biological sex: AllType: InterventionalSponsor: Sherief Abd-ElsalamUpdated: Dec 10, 2018Locations: 1
Eligibility criteria

Rheumatoid arthritis.

Pregnant or lactating [+1]

Status: Recruiting

Effect of Some Drugs on Liver Fibrosis

Effect of Some Drugs on Liver Fibrosis

Participants needed: 45
Trial details
Phase: Phase 3Age: 20+Biological sex: AllType: InterventionalSponsor: Sherief Abd-ElsalamUpdated: Dec 10, 2018Locations: 1
Eligibility criteria

chronic hepatitis C

Acute hepatitis [+1]

Status: Recruiting

Effect of Some Drugs on Rheumatoid Arithritis Activity

Effect of Some Drugs on Rheumatoid Arithritis Activity.

Participants needed: 75
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Sherief Abd-ElsalamUpdated: Dec 10, 2018Locations: 1
Eligibility criteria

Rheumatoid arthritis

liver or renal disease

Status: Recruiting

PPI Versus Histamine Antagnists as Adjuvant to Chemotherapy

The study is a Comparative Clinical and Biochemical Study Evaluating the effect of Proton Pump I nhibitors versus histamine 2 Receptor antagonists as an adjuvant with chemotherapy in patients with Non-hodgkin Lymphoma.

Participants needed: 60
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Sherief Abd-ElsalamUpdated: Aug 27, 2018Locations: 1
Eligibility criteria

DLBCL Lymphoma subtype --No comorbid disease

Pregnancy [+3]