Clinical trials

3

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Study of TRX-100 Tablets Evaluating the Safety, Pharmacokinetics, and Food Effect in Healthy Volunteers

This is a Phase 1b, randomized, double-blind, placebo-controlled, dose escalation study of TRX-100 tablets evaluating the safety, pharmacokinetics, and food effect of single ascending doses of TRX-100 in healthy volunteers.

Participants needed: 24
Trial details
Phase: Phase 1Age: 18-65Biological sex: AllType: InterventionalSponsor: Traws Pharma, Inc.Updated: Apr 13, 2026Locations: 1
Eligibility criteria

Must have given written informed consent before any study-related activities are... [+13]

History or presence of significant cardiovascular, pulmonary, hepatic, renal, ha... [+23]

Status: Not yet recruiting

Phase 2a Study of the Efficacy and Safety of TRX-100 in a Human Influenza A Challenge Model

This will be a randomized, double-blind, placebo-controlled proof of concept study to evaluate the prophylactic efficacy and safety of orally administered TRX-100 in healthy adults challenged with influenza A/France/759/2021 (H1N1) virus.

Participants needed: 165
Trial details
Phase: Phase 2Age: 18-55Biological sex: AllType: InterventionalSponsor: Traws Pharma, Inc.Updated: Mar 31, 2026Locations: 1
Eligibility criteria

Written informed consent signed and dated by the participant and the PI/investig... [+9]

History of, or currently active, symptoms or signs suggestive of upper or lower... [+26]

Status: Recruiting

Early-stage Trial to Determine a Safe and Effective Dose for Ratutrelvir in Patients With Mild to Moderate COVID-19

This is an Early-stage Clinical Trial to Determine a Safe and Effective Dose for Ratutrelvir in Patients With Mild to Moderate COVID-19. It will also learn about the safety of drug Ratutrelvir. Participants will take a study drug as well as a standard therapy. A descriptive statistics will be used to present the study results.

Participants needed: 90
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Traws Pharma, Inc.Updated: Jan 21, 2026Locations: 15
Eligibility criteria

Confirmed SARS-CoV-2 infection for 120 h prior to randomization. [+1]

History, current need for hospitalization or anticipated need for hospitalizatio... [+8]